When the Circadian Clock Meets the Melanin Pigmentary System

Andrzej T. Slominski, Rüdiger Hardeland, Russel J. Reiter

Producción científica: Comment/debaterevisión exhaustiva

16 Citas (Scopus)

Resumen

Silencing of BMAL1 and PER1 stimulates melanogenic activity of follicular and epidermal melanocytes, indicating a novel role for peripheral circadian clock processes in the regulation of melanin pigmentation. Linking the expression levels of BMAL1PER1 with changes in melanogenesis opens exciting opportunities to study the role of the local molecular clock in modulation of melanocyte functions in the hair follicle and the epidermis with attendant effects on epidermal barrier functions in general.

Idioma originalEnglish (US)
Páginas (desde-hasta)943-945
Número de páginas3
PublicaciónJournal of Investigative Dermatology
Volumen135
N.º4
DOI
EstadoPublished - abr 20 2015

ASJC Scopus subject areas

  • Dermatology
  • Molecular Biology
  • Biochemistry
  • Cell Biology

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