Resumen
The low-molecular peptide fractions are obtained from the brain of experimental and control animals by the method which includes sedimentation of high-molecular compounds and gel-filtration on Sephadex G-10. Ischemia of the rat brain sharply changes the amino acidic composition of the isolated peptide fractions. An inhibitory effect of the studied fractions on the activity of DNA-dependent RNA polymerase as well as their effect on the heat denaturation of exogenous DNA are established.
Título traducido de la contribución | Isolation and characteristics of peptide fractions from the rat brain in ischemia |
---|---|
Idioma original | Russian |
Páginas (desde-hasta) | 13-17 |
Número de páginas | 5 |
Publicación | Ukrainski¿ biokhimicheski¿ zhurnal |
Volumen | 57 |
N.º | 6 |
Estado | Published - nov 1985 |
Publicado de forma externa | Sí |
ASJC Scopus subject areas
- Biochemistry