Viral-associated trichodysplasia in a patient with lymphoma: A case report and review

Sandra S. Osswald, Kevin B. Kulick, Maria Magdalena Tomaszewski, Leonard C. Sperling

Producción científica: Review articlerevisión exhaustiva

49 Citas (Scopus)

Resumen

Viral-associated trichodysplasia is a recently described entity associated with immunosuppression. We describe a 68-year-old man with a history of treated lymphoma who developed numerous, disfiguring, papular and spiny lesions involving most of the central face. Both facial and body alopecia was noted. Histopathologic findings of a facial papule showed dramatic alterations of the hair bulbs, including bulbar distention, lack of hair shaft formation and a marked expansion of inner root sheath type epithelium. These findings were identical to those of previously described cases, so electron microscopy was performed. Numerous intranuclear virus particles were identified. Shortly after the diagnosis of trichodysplasia was made, the patient was found to have a relapse of his lymphoma, which may represent the source of his immunosuppression. Based on his skin biopsy findings, successful antiviral therapy was initiated. This case and a review of previously reported cases are discussed in this study.

Idioma originalEnglish (US)
Páginas (desde-hasta)721-725
Número de páginas5
PublicaciónJournal of Cutaneous Pathology
Volumen34
N.º9
DOI
EstadoPublished - sept 2007

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Histology
  • Dermatology

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