Varieties of barbiturate-induced suppression burst activity in the cat

J. Eric Jordan, Terry M. Mikiten, Sterling T. Grice

Resultado de la investigación: Articlerevisión exhaustiva

3 Citas (Scopus)


Activity that appears to be analogous to human suppression burst activity was produced and studied in 11 cats. Three distinct types of activity were identified and arbitrarily labeled as types A, B, and C. Each showed a regular pattern of appearance and disappearance, as well as differential susceptibility to block by barbiturate. Type A was rhythmic activity resembling barbiturate spindles appearing in the early and late stages of a suppression burst episode. It was especially prominent after pentobarbital. Type B activity generally resembled ongoing background activity, except that it was periodically interrupted by brief periods of EEG suppression. Type C activity, brief pleomorphic spike bursts, dominated the EEG and was seen best against a virtually isoelectric recording. It was most resistant to suppression by barbiturate and disappeared from the spontaneous EEG. We suggest that suppression burst as ordinarily conceived is not a single EEG entity but has a substructure which deserves further study.

Idioma originalEnglish (US)
Páginas (desde-hasta)121-135
Número de páginas15
PublicaciónExperimental Neurology
EstadoPublished - ago. 1978

ASJC Scopus subject areas

  • Neurology
  • Developmental Neuroscience


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