Use of cyclotron produced oxygen-15 to study oxygen carrying capacity of free and liposome encapsulated hemoglobin

W. T. Phillips; L. Dixon; R. Klipper; A. S. Rudolph; R. Cliff; M. E. Emch; P. A. Jerabek; C. C. Martin; P. T. Fox; B. Goins

Use of cyclotron produced oxygen-15 to study oxygen carrying capacity of free and liposome encapsulated hemoglobin

W. T. Phillips, L. Dixon, R. Klipper, A. S. Rudolph, R. Cliff, M. E. Emch, P. A. Jerabek, C. C. Martin, P. T. Fox, B. Goins

Producción científica: Conference article › revisión exhaustiva

Resumen

A new method to study the uptake of oxygen from the lungs is demonstrated. The method uses the short lived positron emitting isotope, oxygen-15. Four formulations were studied in four rats each: liposome encapsulated bovine hemoglobin (LEBH), liposome encapsulated human hemolysate (LEHH), free bovine hemoglobin (HEM), and a control saline solution (SAL). The studies demonstrate the feasibility of using this method to assess the oxygen carrying capacity of various blood substitutes.

Idioma original	English (US)
Páginas (desde-hasta)	A145
Publicación	Artificial Cells, Blood Substitutes, and Immobilization Biotechnology
Volumen	22
N.º	5
Estado	Published - nov 1994
Evento	Proceedings of the 11th Congress of the International Society for Artificial Cells, Blood Substitutes and Immobilization Biotechnology, (ISABI) - Boston, MA, USA Duración: jul 24 1994 → jul 27 1994

ASJC Scopus subject areas

Biotechnology
Biomedical Engineering

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@article{cb0079afae9b400e94ddb6b12f20fa66,

title = "Use of cyclotron produced oxygen-15 to study oxygen carrying capacity of free and liposome encapsulated hemoglobin",

abstract = "A new method to study the uptake of oxygen from the lungs is demonstrated. The method uses the short lived positron emitting isotope, oxygen-15. Four formulations were studied in four rats each: liposome encapsulated bovine hemoglobin (LEBH), liposome encapsulated human hemolysate (LEHH), free bovine hemoglobin (HEM), and a control saline solution (SAL). The studies demonstrate the feasibility of using this method to assess the oxygen carrying capacity of various blood substitutes.",

author = "Phillips, {W. T.} and L. Dixon and R. Klipper and Rudolph, {A. S.} and R. Cliff and Emch, {M. E.} and Jerabek, {P. A.} and Martin, {C. C.} and Fox, {P. T.} and B. Goins",

year = "1994",

month = nov,

language = "English (US)",

volume = "22",

pages = "A145",

journal = "Artificial Cells, Blood Substitutes, and Immobilization Biotechnology",

issn = "1073-1199",

publisher = "Informa Healthcare",

number = "5",

note = "Proceedings of the 11th Congress of the International Society for Artificial Cells, Blood Substitutes and Immobilization Biotechnology, (ISABI) ; Conference date: 24-07-1994 Through 27-07-1994",

}

TY - JOUR

T1 - Use of cyclotron produced oxygen-15 to study oxygen carrying capacity of free and liposome encapsulated hemoglobin

AU - Phillips, W. T.

AU - Dixon, L.

AU - Klipper, R.

AU - Rudolph, A. S.

AU - Cliff, R.

AU - Emch, M. E.

AU - Jerabek, P. A.

AU - Martin, C. C.

AU - Fox, P. T.

AU - Goins, B.

PY - 1994/11

Y1 - 1994/11

N2 - A new method to study the uptake of oxygen from the lungs is demonstrated. The method uses the short lived positron emitting isotope, oxygen-15. Four formulations were studied in four rats each: liposome encapsulated bovine hemoglobin (LEBH), liposome encapsulated human hemolysate (LEHH), free bovine hemoglobin (HEM), and a control saline solution (SAL). The studies demonstrate the feasibility of using this method to assess the oxygen carrying capacity of various blood substitutes.

AB - A new method to study the uptake of oxygen from the lungs is demonstrated. The method uses the short lived positron emitting isotope, oxygen-15. Four formulations were studied in four rats each: liposome encapsulated bovine hemoglobin (LEBH), liposome encapsulated human hemolysate (LEHH), free bovine hemoglobin (HEM), and a control saline solution (SAL). The studies demonstrate the feasibility of using this method to assess the oxygen carrying capacity of various blood substitutes.

UR - http://www.scopus.com/inward/record.url?scp=0028533622&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0028533622&partnerID=8YFLogxK

M3 - Conference article

AN - SCOPUS:0028533622

SN - 1073-1199

VL - 22

SP - A145

JO - Artificial Cells, Blood Substitutes, and Immobilization Biotechnology

JF - Artificial Cells, Blood Substitutes, and Immobilization Biotechnology

IS - 5

T2 - Proceedings of the 11th Congress of the International Society for Artificial Cells, Blood Substitutes and Immobilization Biotechnology, (ISABI)

Y2 - 24 July 1994 through 27 July 1994

ER -

Use of cyclotron produced oxygen-15 to study oxygen carrying capacity of free and liposome encapsulated hemoglobin

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