T2 hyperintense foci on magnetic resonance images of schizophrenic patients and controls

George Bartzokis; H. Jordan Garber; Virginia J. Griswold; William H. Oldendorf; Jim Mintz; Stephen R. Marder

doi:10.1016/0925-4927(91)90015-I

T₂ hyperintense foci on magnetic resonance images of schizophrenic patients and controls

George Bartzokis, H. Jordan Garber, Virginia J. Griswold, William H. Oldendorf, Jim Mintz, Stephen R. Marder

Resultado de la investigación: Article › revisión exhaustiva

8 Citas (Scopus)

Resumen

High resolution magnetic resonance imaging (MRI) of the brain was performed on 18 male schizophrenic patients and 15 male normal control subjects using an identical imaging protocol. The number and size of T₂ hyperintense foci were clinically quantified by an academic radiologist. Large foci (≥ 3 mm in diameter) were observed more frequently on patient images ( 7 18) than on control images ( 1 15). The imaging protocol detected high rates of focal hyperintensities, but no differences between patients and controls were noted in the total affected brain area (sum of focal areas) or in the presence or absence of foci.

Idioma original	English (US)
Páginas (desde-hasta)	239-245
Número de páginas	7
Publicación	Psychiatry Research: Neuroimaging
Volumen	40
N.º	4
DOI	https://doi.org/10.1016/0925-4927(91)90015-I
Estado	Published - dic. 1991
Publicado de forma externa	Sí

ASJC Scopus subject areas

Neuroscience (miscellaneous)
Radiology Nuclear Medicine and imaging
Psychiatry and Mental health

Acceder al documento

10.1016/0925-4927(91)90015-I

Otros archivos y enlaces

Citar esto

@article{6ae5effc3b4e41f4b37870c99b85874e,

title = "T2 hyperintense foci on magnetic resonance images of schizophrenic patients and controls",

abstract = "High resolution magnetic resonance imaging (MRI) of the brain was performed on 18 male schizophrenic patients and 15 male normal control subjects using an identical imaging protocol. The number and size of T2 hyperintense foci were clinically quantified by an academic radiologist. Large foci (≥ 3 mm in diameter) were observed more frequently on patient images ( 7 18) than on control images ( 1 15). The imaging protocol detected high rates of focal hyperintensities, but no differences between patients and controls were noted in the total affected brain area (sum of focal areas) or in the presence or absence of foci.",

keywords = "Magnetic resonance imaging, T hyperintense foci, schizophrenia, tardive dyskinesia",

author = "George Bartzokis and Garber, {H. Jordan} and Griswold, {Virginia J.} and Oldendorf, {William H.} and Jim Mintz and Marder, {Stephen R.}",

note = "Funding Information: Acknowledgments. This work was supported by the Research Service, Department of Veterans Affairs, National Alliance for Research on Schilophrenia and Depression, National Institute of Mental Health grant M H-14584 and 5T32-M H-17140. The authors are grateful to Diane Osborne, Thomas Ellis, and Loren Sachs for MR! technical assistance; to Joseph Tabrisky, Jeffrey Philips, Jeffrey Cummings, Robert P. Liberman, and Michael Goldstein for helpful advice and support; and to Stella Oidendorf and John Williams for assistance in preparing the manuscript.",

year = "1991",

month = dec,

doi = "10.1016/0925-4927(91)90015-I",

language = "English (US)",

volume = "40",

pages = "239--245",

journal = "Psychiatry Research - Neuroimaging",

issn = "0925-4927",

publisher = "Elsevier Ireland Ltd",

number = "4",

}

TY - JOUR

T1 - T2 hyperintense foci on magnetic resonance images of schizophrenic patients and controls

AU - Bartzokis, George

AU - Garber, H. Jordan

AU - Griswold, Virginia J.

AU - Oldendorf, William H.

AU - Mintz, Jim

AU - Marder, Stephen R.

N1 - Funding Information: Acknowledgments. This work was supported by the Research Service, Department of Veterans Affairs, National Alliance for Research on Schilophrenia and Depression, National Institute of Mental Health grant M H-14584 and 5T32-M H-17140. The authors are grateful to Diane Osborne, Thomas Ellis, and Loren Sachs for MR! technical assistance; to Joseph Tabrisky, Jeffrey Philips, Jeffrey Cummings, Robert P. Liberman, and Michael Goldstein for helpful advice and support; and to Stella Oidendorf and John Williams for assistance in preparing the manuscript.

PY - 1991/12

Y1 - 1991/12

N2 - High resolution magnetic resonance imaging (MRI) of the brain was performed on 18 male schizophrenic patients and 15 male normal control subjects using an identical imaging protocol. The number and size of T2 hyperintense foci were clinically quantified by an academic radiologist. Large foci (≥ 3 mm in diameter) were observed more frequently on patient images ( 7 18) than on control images ( 1 15). The imaging protocol detected high rates of focal hyperintensities, but no differences between patients and controls were noted in the total affected brain area (sum of focal areas) or in the presence or absence of foci.

AB - High resolution magnetic resonance imaging (MRI) of the brain was performed on 18 male schizophrenic patients and 15 male normal control subjects using an identical imaging protocol. The number and size of T2 hyperintense foci were clinically quantified by an academic radiologist. Large foci (≥ 3 mm in diameter) were observed more frequently on patient images ( 7 18) than on control images ( 1 15). The imaging protocol detected high rates of focal hyperintensities, but no differences between patients and controls were noted in the total affected brain area (sum of focal areas) or in the presence or absence of foci.

KW - Magnetic resonance imaging

KW - T hyperintense foci

KW - schizophrenia

KW - tardive dyskinesia

UR - http://www.scopus.com/inward/record.url?scp=0026341315&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0026341315&partnerID=8YFLogxK

U2 - 10.1016/0925-4927(91)90015-I

DO - 10.1016/0925-4927(91)90015-I

M3 - Article

C2 - 1811241

AN - SCOPUS:0026341315

VL - 40

SP - 239

EP - 245

JO - Psychiatry Research - Neuroimaging

JF - Psychiatry Research - Neuroimaging

SN - 0925-4927

IS - 4

ER -