Trex2 responds to damaged replication forks in diverse ways

Paul Hasty

doi:10.1080/23723556.2021.1881394

Trex2 responds to damaged replication forks in diverse ways

Paul Hasty

Department of Molecular Medicine

Producción científica: Article › revisión exhaustiva

1 Cita (Scopus)

Resumen

Three prime Repair Exonuclease 2 (Trex2) alters replication fork (RF) stability and mutation levels in cells defective for homologous recombination (HR). Trex2 has multiple functions that can either cause or supress RF instability in cells with different HR-defects. Why does Trex2 have such diverse effects on RF maintenance?.

Idioma original	English (US)
Número de artículo	1881394
Publicación	Molecular and Cellular Oncology
Volumen	8
N.º	2
DOI	https://doi.org/10.1080/23723556.2021.1881394
Estado	Published - 2021

ASJC Scopus subject areas

Molecular Medicine
Cancer Research

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title = "Trex2 responds to damaged replication forks in diverse ways",

abstract = "Three prime Repair Exonuclease 2 (Trex2) alters replication fork (RF) stability and mutation levels in cells defective for homologous recombination (HR). Trex2 has multiple functions that can either cause or supress RF instability in cells with different HR-defects. Why does Trex2 have such diverse effects on RF maintenance?.",

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Trex2 responds to damaged replication forks in diverse ways

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