Tie Me Up, Tie Me Down: Inhibiting RNA Polymerase

Rui Sousa

doi:10.1016/j.cell.2008.09.052

Tie Me Up, Tie Me Down: Inhibiting RNA Polymerase

Rui Sousa

Department of Biochemistry & Structural Biology

Resultado de la investigación: Short survey › revisión exhaustiva

10 Citas (Scopus)

Resumen

Mechanistic understanding of antibiotic action can yield crucial insights that aid in the design of new antibiotics. In this issue, Mukhopadhyay et al. (2008) uncover the mechanism by which the antibiotic myxopyronin inhibits bacterial RNA polymerase, suggesting a new target region in RNA polymerase for inhibitor design.

Idioma original	English (US)
Páginas (desde-hasta)	205-207
Número de páginas	3
Publicación	Cell
Volumen	135
N.º	2
DOI	https://doi.org/10.1016/j.cell.2008.09.052
Estado	Published - oct 17 2008

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)

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10.1016/j.cell.2008.09.052

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abstract = "Mechanistic understanding of antibiotic action can yield crucial insights that aid in the design of new antibiotics. In this issue, Mukhopadhyay et al. (2008) uncover the mechanism by which the antibiotic myxopyronin inhibits bacterial RNA polymerase, suggesting a new target region in RNA polymerase for inhibitor design.",

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Tie Me Up, Tie Me Down: Inhibiting RNA Polymerase

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ASJC Scopus subject areas

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