The southwest oncology group experience: adjuvant therapy for stage IB and II non-seminomatous testicular cancer

Ronald L. Stephens; James R. Eltringham; Charles A. Coltman; James Neidhart; James Mullins; Jess Frank

doi:10.1016/0360-3016(83)90357-7

The southwest oncology group experience: adjuvant therapy for stage IB and II non-seminomatous testicular cancer

Ronald L. Stephens, James R. Eltringham, Charles A. Coltman, James Neidhart, James Mullins, Jess Frank

Resultado de la investigación: Article › revisión exhaustiva

Resumen

During a two year period, 65 patients with Stage II non-seminomatous testis cancer were randomized to receive adjuvant chemotherapy and radiation. Of the 52 evaluable patients, 23 received radiation followed by chemotherapy (sequential), and 29 received the same chemotherapy as initial treatment, but had drug treatment temporarily interrupted for radiation (sandwich). The combined treatment was well tolerated, but did not eliminate recurrence. With regard to duration of survival and disease-free survival, no statistically significant difference could be found between the sequential and sandwich approaches.

Idioma original	English (US)
Páginas (desde-hasta)	1885-1890
Número de páginas	6
Publicación	International journal of radiation oncology, biology, physics
Volumen	9
N.º	12
DOI	https://doi.org/10.1016/0360-3016(83)90357-7
Estado	Published - dic 1983
Publicado de forma externa	Sí

ASJC Scopus subject areas

Radiation
Oncology
Radiology Nuclear Medicine and imaging
Cancer Research

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title = "The southwest oncology group experience: adjuvant therapy for stage IB and II non-seminomatous testicular cancer",

abstract = "During a two year period, 65 patients with Stage II non-seminomatous testis cancer were randomized to receive adjuvant chemotherapy and radiation. Of the 52 evaluable patients, 23 received radiation followed by chemotherapy (sequential), and 29 received the same chemotherapy as initial treatment, but had drug treatment temporarily interrupted for radiation (sandwich). The combined treatment was well tolerated, but did not eliminate recurrence. With regard to duration of survival and disease-free survival, no statistically significant difference could be found between the sequential and sandwich approaches.",

keywords = "Adjuvant treatment, Testis cancer",

author = "Stephens, {Ronald L.} and Eltringham, {James R.} and Coltman, {Charles A.} and James Neidhart and James Mullins and Jess Frank",

note = "Funding Information: {\textquoteleft}University of Texas Health Sciences Center at San Antonio. 40hio State University Hospital. {\textquoteleft}Wilford Hall Medical Center. %outhwest Oncology Group Biostatistical Center Houston, TX. This investigation was supported in part by the following PHS grant numbers awarded by the National Cancer Institute, DHHS: CA-l 2644, CA-I 3238, CA-22433, CA-04920, CA-",

year = "1983",

month = dec,

doi = "10.1016/0360-3016(83)90357-7",

language = "English (US)",

volume = "9",

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AU - Coltman, Charles A.

AU - Neidhart, James

AU - Mullins, James

AU - Frank, Jess

N1 - Funding Information: ‘University of Texas Health Sciences Center at San Antonio. 40hio State University Hospital. ‘Wilford Hall Medical Center. %outhwest Oncology Group Biostatistical Center Houston, TX. This investigation was supported in part by the following PHS grant numbers awarded by the National Cancer Institute, DHHS: CA-l 2644, CA-I 3238, CA-22433, CA-04920, CA-

PY - 1983/12

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N2 - During a two year period, 65 patients with Stage II non-seminomatous testis cancer were randomized to receive adjuvant chemotherapy and radiation. Of the 52 evaluable patients, 23 received radiation followed by chemotherapy (sequential), and 29 received the same chemotherapy as initial treatment, but had drug treatment temporarily interrupted for radiation (sandwich). The combined treatment was well tolerated, but did not eliminate recurrence. With regard to duration of survival and disease-free survival, no statistically significant difference could be found between the sequential and sandwich approaches.

AB - During a two year period, 65 patients with Stage II non-seminomatous testis cancer were randomized to receive adjuvant chemotherapy and radiation. Of the 52 evaluable patients, 23 received radiation followed by chemotherapy (sequential), and 29 received the same chemotherapy as initial treatment, but had drug treatment temporarily interrupted for radiation (sandwich). The combined treatment was well tolerated, but did not eliminate recurrence. With regard to duration of survival and disease-free survival, no statistically significant difference could be found between the sequential and sandwich approaches.

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The southwest oncology group experience: adjuvant therapy for stage IB and II non-seminomatous testicular cancer

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