The role of nerve monitoring to predict postoperative recurrent laryngeal nerve function in thyroid and parathyroid surgery

Issam Eid, Frank R. Miller, Stephanie Rowan, Randal A. Otto

Producción científica: Articlerevisión exhaustiva

19 Citas (Scopus)


Objectives/Hypothesis To determine the role and efficacy of intraoperative recurrent laryngeal nerve (RLN) stimulation in the prediction of early and permanent postoperative nerve function in thyroid and parathyroid surgery. Study Design A retrospective review of thyroid and parathyroid surgeries was performed with calculation of sensitivity and specificity of the response of intraoperative stimulation for different pathological groups. Methods Normal electromyography (EMG) response with 0.5 mAmp stimulation was considered a positive stimulation response with postoperative function determined by laryngoscopy. No EMG response at >1-2 mAmps was considered a negative response. The rates of early and permanent paralysis, as well as sensitivity, specificity, and positive and negative predictive values for postoperative nerve function were calculated for separate pathological groups. Results The number of nerves at risk analyzed was 909. The overall early and permanent paralysis rates were 3.1% and 1.2%, respectively, with the highest rate being for Grave's disease cases. The overall sensitivity was 98.4%. The specificity was lower at 62.5% but acceptable in thyroid carcinoma and Grave's disease patients. The majority of nerves with a positive stimulation result and postoperative paralysis on laryngoscopy recovered function in 3 to 12 weeks, showing positive stimulation to be a good predictor of eventual recovery. Conclusions Stimulation of the RLN during thyroid and parathyroid surgery is a useful tool in predicting postoperative RLN function. The sensitivity of stimulation is high, showing positive stimulation to be an excellent predictor of normal nerve function. Negative stimulation is more predictive of paralysis in cases of thyroid carcinoma and Grave's disease. Level of Evidence 2b. Laryngoscope, 123:2584-2587, 2013

Idioma originalEnglish (US)
Páginas (desde-hasta)2583-2586
Número de páginas4
EstadoPublished - oct 2013

ASJC Scopus subject areas

  • Otorhinolaryngology


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