The relationship between salivary histatin levels and oral yeast carriage

A. Jainkittivong, D. A. Johnson, C. K. Yeh

Resultado de la investigación: Articlerevisión exhaustiva

35 Citas (Scopus)

Resumen

Candida species are common commensal inhabitants of the oral cavity. Human saliva contains antifungal proteins called histatins. We tested the hypothesis that oral yeast status is related to salivary histatin levels. Thirty subjects were divided into two groups based on the presence (n= 15) or absence (n= 15) of yeast on oral mucosa surfaces. Unstimulated and stimulated submandibular and sublingual and parotid saliva was collected from each subject. Salivary flow rates were measured and histatin concentrations were determined in the stimulated saliva samples. The yeast colony positive group showed lower median unstimulated parotid saliva flow rates as well as lower median concentrations of total histatins in submandibular and sublingual saliva. There was a negative correlation between yeast colony-forming units and unstimulated parotid saliva flow rates and between yeast colony-forming units and submandibular and sublingual saliva histatin concentration and secretion. The results suggest that oral yeast status may be influenced by unstimulated parotid saliva flow rates and by submandibular and sublingual histatin concentration and secretion.

Idioma originalEnglish (US)
Páginas (desde-hasta)181-187
Número de páginas7
PublicaciónOral Microbiology and Immunology
Volumen13
N.º3
DOI
EstadoPublished - jun. 1998

ASJC Scopus subject areas

  • Microbiology
  • Immunology
  • Dentistry(all)
  • Microbiology (medical)

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