TY - JOUR
T1 - The management of community-acquired pneumonia in the elderly
AU - Faverio, Paola
AU - Aliberti, Stefano
AU - Bellelli, Giuseppe
AU - Suigo, Giulia
AU - Lonni, Sara
AU - Pesci, Alberto
AU - Restrepo, Marcos I.
N1 - Funding Information:
The authors have no conflicts of interests to declare related to this manuscript. Dr Restrepo time is partially protected by Award Number K23HL096054 from the National Heart, Lung, and Blood Institute . The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Heart, Lung, and Blood Institute or the National Institutes of Health. The funding agencies had no role in the preparation, review, or approval of the manuscript. The views expressed in this article are those of the author and do not necessarily represent the views of the Department of Veterans Affairs.
PY - 2014/4
Y1 - 2014/4
N2 - Pneumonia is one of the main causes of morbidity and mortality in the elderly. The elderly population has exponentially increased in the last decades and the current epidemiological trends indicate that it is expected to further increase. Therefore, recognizing the special needs of older people is of paramount importance. In this review we address the main differences between elderly and adult patients with pneumonia. We focus on several aspects, including the atypical clinical presentation of pneumonia in the elderly, the methods to assess severity of illness, the appropriate setting of care, and the management of comorbidities. We also discuss how to approach the common complications of severe pneumonia, including acute respiratory failure and severe sepsis. Moreover, we debate whether or not elderly patients are at higher risk of infection due to multi-drug resistant pathogens and which risk factors should be considered when choosing the antibiotic therapy. We highlight the differences in the definition of clinical stability and treatment failure between adults and elderly patients. Finally, we review the main outcomes, preventive and supportive measures to be considered in elderly patients with pneumonia.
AB - Pneumonia is one of the main causes of morbidity and mortality in the elderly. The elderly population has exponentially increased in the last decades and the current epidemiological trends indicate that it is expected to further increase. Therefore, recognizing the special needs of older people is of paramount importance. In this review we address the main differences between elderly and adult patients with pneumonia. We focus on several aspects, including the atypical clinical presentation of pneumonia in the elderly, the methods to assess severity of illness, the appropriate setting of care, and the management of comorbidities. We also discuss how to approach the common complications of severe pneumonia, including acute respiratory failure and severe sepsis. Moreover, we debate whether or not elderly patients are at higher risk of infection due to multi-drug resistant pathogens and which risk factors should be considered when choosing the antibiotic therapy. We highlight the differences in the definition of clinical stability and treatment failure between adults and elderly patients. Finally, we review the main outcomes, preventive and supportive measures to be considered in elderly patients with pneumonia.
KW - Acute respiratory failure
KW - Antibiotic treatment
KW - Community-acquired pneumonia
KW - Elderly
KW - Functional status
KW - Severity
UR - http://www.scopus.com/inward/record.url?scp=84899982068&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84899982068&partnerID=8YFLogxK
U2 - 10.1016/j.ejim.2013.12.001
DO - 10.1016/j.ejim.2013.12.001
M3 - Review article
C2 - 24360244
AN - SCOPUS:84899982068
SN - 0953-6205
VL - 25
SP - 312
EP - 319
JO - European Journal of Internal Medicine
JF - European Journal of Internal Medicine
IS - 4
ER -