The effects of repeated Ozurdex injections on ocular hypertension

Sepehr Bahadorani, Chelsey Krambeer, Kendall Wannamaker, Wayne Tie, Michael Jansen, Jason Espitia, Jeong Hyeon Sohn, Michael A. Singer

Resultado de la investigación: Articlerevisión exhaustiva

20 Citas (Scopus)

Resumen

Purpose: The purpose of this study was to correlate the degree of ocular hypertension with the number of Ozurdex injections. Methods: Intraocular pressure (IOP) fluctuations for a total of 183 injections were studied over a period of at least 12 months. The main indications for treatment were uveitis, diabetic macular edema, and retinal vein occlusion. Results: Results of the study demonstrate that repeated Ozurdex injections do not increase the frequency of IOP spikes beyond 30 mmHg. For lower IOPs, however, a positive correlation exists. Furthermore, patients with primary open angle glaucoma and uveitis had the highest IOP response to repeated injections. On average, patients with an IOP of ≥28.6 mmHg received pressure lowering medications, after which their IOP reached a stable level (16.7 mmHg) without the need for additional interventions. Conclusion: The data support the conclusion that multiple Ozurdex injections does not increase the frequency of IOP spikes beyond 30 mmHg, but patients still must be closely monitored if they have a history of primary open angle glaucoma.

Idioma originalEnglish (US)
Páginas (desde-hasta)639-642
Número de páginas4
PublicaciónClinical Ophthalmology
Volumen12
DOI
EstadoPublished - abr 3 2018

ASJC Scopus subject areas

  • Ophthalmology

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