TY - JOUR
T1 - The 2022 symposium on dementia and brain aging in low- and middle-income countries
T2 - Highlights on research, diagnosis, care, and impact
AU - Kalaria, Raj
AU - Maestre, Gladys
AU - Mahinrad, Simin
AU - Acosta, Daisy M.
AU - Akinyemi, Rufus Olusola
AU - Alladi, Suvarna
AU - Allegri, Ricardo F.
AU - Arshad, Faheem
AU - Babalola, David Oluwasayo
AU - Baiyewu, Olusegun
AU - Bak, Thomas H.
AU - Bellaj, Tarek
AU - Brodie-Mends, David K.
AU - Carrillo, Maria C.
AU - Celestin, Kaputu Kalala Malu
AU - Damasceno, Albertino
AU - de Silva, Ranil Karunamuni
AU - de Silva, Rohan
AU - Djibuti, Mamuka
AU - Dreyer, Anna Jane
AU - Ellajosyula, Ratnavalli
AU - Farombi, Temitope H.
AU - Friedland, Robert P.
AU - Garza, Noe
AU - Gbessemehlan, Antoine
AU - Georgiou, Eliza Eleni Zacharoula
AU - Govia, Ishtar
AU - Grinberg, Lea T.
AU - Guerchet, Maëlenn
AU - Gugssa, Seid Ali
AU - Gumikiriza-Onoria, Joy Louise
AU - Hogervorst, Eef
AU - Hornberger, Michael
AU - Ibanez, Agustin
AU - Ihara, Masafumi
AU - Issac, Thomas Gregor
AU - Jönsson, Linus
AU - Karanja, Wambui M.
AU - Lee, Joseph H.
AU - Leroi, Iracema
AU - Livingston, Gill
AU - Manes, Facundo Francisco
AU - Mbakile-Mahlanza, Lingani
AU - Miller, Bruce L.
AU - Musyimi, Christine Wayua
AU - Mutiso, Victoria N.
AU - Nakasujja, Noeline
AU - Ndetei, David M.
AU - Nightingale, Sam
AU - Novotni, Gabriela
AU - Nyamayaro, Primrose
AU - Nyame, Solomon
AU - Ogeng'o, Julius A.
AU - Ogunniyi, Adesola
AU - de Oliveira, Maira Okada
AU - Okubadejo, Njideka U.
AU - Orrell, Martin
AU - Paddick, Stella Maria
AU - Pericak-Vance, Margaret A.
AU - Pirtosek, Zvezdan
AU - Potocnik, Felix Claude Victor
AU - Raman, Rema
AU - Rizig, Mie
AU - Rosselli, Mónica
AU - Salokhiddinov, Marufjon
AU - Satizabal, Claudia L.
AU - Sepulveda-Falla, Diego
AU - Seshadri, Sudha
AU - Sexton, Claire E.
AU - Skoog, Ingmar
AU - George-Hyslop, Peter H.St
AU - Suemoto, Claudia Kimie
AU - Thapa, Prekshy
AU - Udeh-Momoh, Chinedu Theresa
AU - Valcour, Victor
AU - Vance, Jeffery M.
AU - Varghese, Mathew
AU - Vera, Jaime H.
AU - Walker, Richard W.
AU - Zetterberg, Henrik
AU - Zewde, Yared Z.
AU - Ismail, Ozama
N1 - Publisher Copyright:
© 2024 The Authors. Alzheimer's & Dementia published by Wiley Periodicals LLC on behalf of Alzheimer's Association.
PY - 2024/6
Y1 - 2024/6
N2 - Two of every three persons living with dementia reside in low- and middle-income countries (LMICs). The projected increase in global dementia rates is expected to affect LMICs disproportionately. However, the majority of global dementia care costs occur in high-income countries (HICs), with dementia research predominantly focusing on HICs. This imbalance necessitates LMIC-focused research to ensure that characterization of dementia accurately reflects the involvement and specificities of diverse populations. Development of effective preventive, diagnostic, and therapeutic approaches for dementia in LMICs requires targeted, personalized, and harmonized efforts. Our article represents timely discussions at the 2022 Symposium on Dementia and Brain Aging in LMICs that identified the foremost opportunities to advance dementia research, differential diagnosis, use of neuropsychometric tools, awareness, and treatment options. We highlight key topics discussed at the meeting and provide future recommendations to foster a more equitable landscape for dementia prevention, diagnosis, care, policy, and management in LMICs. Highlights: Two-thirds of persons with dementia live in LMICs, yet research and costs are skewed toward HICs. LMICs expect dementia prevalence to more than double, accompanied by socioeconomic disparities. The 2022 Symposium on Dementia in LMICs addressed advances in research, diagnosis, prevention, and policy. The Nairobi Declaration urges global action to enhance dementia outcomes in LMICs.
AB - Two of every three persons living with dementia reside in low- and middle-income countries (LMICs). The projected increase in global dementia rates is expected to affect LMICs disproportionately. However, the majority of global dementia care costs occur in high-income countries (HICs), with dementia research predominantly focusing on HICs. This imbalance necessitates LMIC-focused research to ensure that characterization of dementia accurately reflects the involvement and specificities of diverse populations. Development of effective preventive, diagnostic, and therapeutic approaches for dementia in LMICs requires targeted, personalized, and harmonized efforts. Our article represents timely discussions at the 2022 Symposium on Dementia and Brain Aging in LMICs that identified the foremost opportunities to advance dementia research, differential diagnosis, use of neuropsychometric tools, awareness, and treatment options. We highlight key topics discussed at the meeting and provide future recommendations to foster a more equitable landscape for dementia prevention, diagnosis, care, policy, and management in LMICs. Highlights: Two-thirds of persons with dementia live in LMICs, yet research and costs are skewed toward HICs. LMICs expect dementia prevalence to more than double, accompanied by socioeconomic disparities. The 2022 Symposium on Dementia in LMICs addressed advances in research, diagnosis, prevention, and policy. The Nairobi Declaration urges global action to enhance dementia outcomes in LMICs.
KW - Alzheimer's disease
KW - dementia
KW - diversity
KW - high-income countries
KW - low- and middle-income countries
KW - risk factors
KW - vascular dementia
UR - http://www.scopus.com/inward/record.url?scp=85191870246&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85191870246&partnerID=8YFLogxK
U2 - 10.1002/alz.13836
DO - 10.1002/alz.13836
M3 - Review article
C2 - 38696263
AN - SCOPUS:85191870246
SN - 1552-5260
VL - 20
SP - 4290
EP - 4314
JO - Alzheimer's and Dementia
JF - Alzheimer's and Dementia
IS - 6
ER -