Resumen
A novel three-component cascade reaction was discovered and developed to synthesize pyridodiindoles with the assistance of microwave irradiation. A collection of pyridodiindoles was prepared by means of the mild reaction and simple operation procedure, which could be applicable to a broad scope of functional aldehydes. Screening demonstrated that compound 5g exhibited a good potency in HCT116 cell lines, and this work validated the feasibility of this novel reaction for generating promising bioactive compounds.
Idioma original | English (US) |
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Páginas (desde-hasta) | 7811-7815 |
Número de páginas | 5 |
Publicación | Organic Letters |
Volumen | 20 |
N.º | 24 |
DOI | |
Estado | Published - dic 21 2018 |
Publicado de forma externa | Sí |
ASJC Scopus subject areas
- Biochemistry
- Physical and Theoretical Chemistry
- Organic Chemistry