Synaptic vesicle recycling

E. M. Lafer

doi:10.1007/978-0-387-30380-2_21

Synaptic vesicle recycling

E. M. Lafer

Department of Biochemistry & Structural Biology

Producción científica: Chapter

Resumen

The mechanism of synaptic vesicle recycling has been hotly debated for more than 30 years. The various mechanistic models are presented, and the evidence supporting each model is discussed. It is now well accepted that endocytosis rates span an enormous range and are highly dependent on exocytosis rates. It is also well accepted that clathrin-mediated endocytosis plays a major role in synaptic vesicle recycling. However, it remains to be determined whether endocytic pathways with dramatically different rates operate using the same or different molecular mechanisms.

Idioma original	English (US)
Título de la publicación alojada	Handbook of Neurochemistry and Molecular Neurobiology
Subtítulo de la publicación alojada	Neural Membranes and Transport
Editorial	Springer US
Páginas	423-437
Número de páginas	15
ISBN (versión impresa)	9780387303468
DOI	https://doi.org/10.1007/978-0-387-30380-2_21
Estado	Published - 2007

ASJC Scopus subject areas

General Neuroscience
General Biochemistry, Genetics and Molecular Biology

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10.1007/978-0-387-30380-2_21

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abstract = "The mechanism of synaptic vesicle recycling has been hotly debated for more than 30 years. The various mechanistic models are presented, and the evidence supporting each model is discussed. It is now well accepted that endocytosis rates span an enormous range and are highly dependent on exocytosis rates. It is also well accepted that clathrin-mediated endocytosis plays a major role in synaptic vesicle recycling. However, it remains to be determined whether endocytic pathways with dramatically different rates operate using the same or different molecular mechanisms.",

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Synaptic vesicle recycling

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