Surgical resection and amniotic membrane transplantation for treatment of refractory giant papillae in vernal keratoconjunctivitis

Ping Guo, Ahmad Kheirkhah, Wei Wei Zhou, Lei Qin, Xiao Li Shen

Producción científica: Articlerevisión exhaustiva

21 Citas (Scopus)

Resumen

Purpose: The aim of this study was to evaluate the outcome of surgical resection and amniotic membrane transplantation (AMT) for treatment of refractory symptomatic giant papillae in vernal keratoconjunctivitis (VKC). Methods: This is a retrospective study of 13 eyes of 9 patients with refractory giant papillae associated with corneal shield ulcer and/or punctate epithelial erosions who underwent surgical resection of the papillae combined with AMT to cover the tarsal conjunctival defect. Results: During 14.2 ± 4.2 months of postoperative follow-up, smooth tarsal conjunctival surface was achieved in all cases, with no recurrence of the giant papillae in any eye. Corneal shield ulcers and punctate epithelial erosions healed within 2 weeks after surgery and did not recur during the follow-up. Best-corrected visual acuity improved from 0.26 ± 0.21 logarithm of the minimum angle of resolution preoperatively to 0.02 ± 0.04 logarithm of the minimum angle of resolution postoperatively (P = 0.01). Three patients experienced recurrence of VKC symptoms, but without giant papillae, which could be well controlled by topical medications. Conclusions: Surgical resection combined with AMT is an effective procedure for treatment of refractory giant papillae in patients with VKC.

Idioma originalEnglish (US)
Páginas (desde-hasta)816-820
Número de páginas5
PublicaciónCornea
Volumen32
N.º6
DOI
EstadoPublished - jun 2013
Publicado de forma externa

ASJC Scopus subject areas

  • Ophthalmology

Huella

Profundice en los temas de investigación de 'Surgical resection and amniotic membrane transplantation for treatment of refractory giant papillae in vernal keratoconjunctivitis'. En conjunto forman una huella única.

Citar esto