TY - JOUR
T1 - Surgical Predictors of Clinical Outcomes after Revision Anterior Cruciate Ligament Reconstruction
AU - Allen, Christina R.
AU - Anderson, Allen F.
AU - Cooper, Daniel E.
AU - Deberardino, Thomas M.
AU - Dunn, Warren R.
AU - Haas, Amanda K.
AU - Huston, Laura J.
AU - Lantz, Brett A.
AU - Mann, Barton
AU - Nwosu, Sam K.
AU - Spindler, Kurt P.
AU - Stuart, Michael J.
AU - Wright, Rick W.
AU - Albright, John P.
AU - Amendola, Annunziato
AU - Andrish, Jack T.
AU - Annunziata, Christopher C.
AU - Arciero, Robert A.
AU - Bach, Bernard R.
AU - Baker, Champ L.
AU - Bartolozzi, Arthur R.
AU - Baumgarten, Keith M.
AU - Bechler, Jeffery R.
AU - Berg, Jeffrey H.
AU - Bernas, Geoffrey A.
AU - Brockmeier, Stephen F.
AU - Brophy, Robert H.
AU - Bush-Joseph, Charles A.
AU - Butler, J. Brad
AU - Campbell, John D.
AU - Carey, James L.
AU - Carpenter, James E.
AU - Cole, Brian J.
AU - Cooper, Jonathan M.
AU - Cox, Charles L.
AU - Creighton, R. Alexander
AU - Dahm, Diane L.
AU - David, Tal S.
AU - Flanigan, David C.
AU - Frederick, Robert W.
AU - Ganley, Theodore J.
AU - Garofoli, Elizabeth A.
AU - Gatt, Charles J.
AU - Gecha, Steven R.
AU - Giffin, James Robert
AU - Hame, Sharon L.
AU - Hannafin, Jo A.
AU - Harner, Christopher D.
AU - Harris, Norman Lindsay
AU - Hechtman, Keith S.
AU - Hershman, Elliott B.
AU - Hoellrich, Rudolf G.
AU - Hosea, Timothy M.
AU - Johnson, David C.
AU - Johnson, Timothy S.
AU - Jones, Morgan H.
AU - Kaeding, Christopher C.
AU - Kamath, Ganesh V.
AU - Klootwyk, Thomas E.
AU - Levy, Bruce A.
AU - Ma, C. Benjamin
AU - Maiers, G. Peter
AU - Marx, Robert G.
AU - Matava, Matthew J.
AU - Mathien, Gregory M.
AU - McAllister, David R.
AU - McCarty, Eric C.
AU - McCormack, Robert G.
AU - Miller, Bruce S.
AU - Nissen, Carl W.
AU - O'Neill, Daniel F.
AU - Owens, Brett D.
AU - Parker, Richard D.
AU - Purnell, Mark L.
AU - Ramappa, Arun J.
AU - Rauh, Michael A.
AU - Rettig, Arthur C.
AU - Sekiya, Jon K.
AU - Shea, Kevin G.
AU - Sherman, Orrin H.
AU - Slauterbeck, James R.
AU - Smith, Matthew V.
AU - Spang, Jeffrey T.
AU - Svoboda, Steven J.
AU - Taft, Timothy N.
AU - Tenuta, Joachim J.
AU - Tingstad, Edwin M.
AU - Vidal, Armando F.
AU - Viskontas, Darius G.
AU - White, Richard A.
AU - Williams, James S.
AU - Wolcott, Michelle L.
AU - Wolf, Brian R.
AU - York, James J.
N1 - Publisher Copyright:
© 2017 The Author(s).
PY - 2017/9/1
Y1 - 2017/9/1
N2 - Background: Revision anterior cruciate ligament (ACL) reconstruction has been documented to have worse outcomes compared with primary ACL reconstruction. Hypothesis: Certain factors under the control of the surgeon at the time of revision surgery can both negatively and positively affect outcomes. Study Design: Case-control study; Level of evidence, 3. Methods: Patients undergoing revision ACL reconstruction were identified and prospectively enrolled between 2006 and 2011. Data collected included baseline demographics, intraoperative surgical technique and joint disorders, and a series of validated patient-reported outcome instruments (International Knee Documentation Committee [IKDC] subjective form, Knee Injury and Osteoarthritis Outcome Score [KOOS], Western Ontario and McMaster Universities Osteoarthritis Index [WOMAC], and Marx activity rating scale) completed before surgery. Patients were followed up for 2 years and asked to complete an identical set of outcome instruments. Regression analysis was used to control for age, sex, body mass index (BMI), activity level, baseline outcome scores, revision number, time since last ACL reconstruction, and a variety of previous and current surgical variables to assess the surgical risk factors for clinical outcomes 2 years after revision ACL reconstruction. Results: A total of 1205 patients (697 male [58%]) met the inclusion criteria and were successfully enrolled. The median age was 26 years, and the median time since their last ACL reconstruction was 3.4 years. Two-year follow-up was obtained on 82% (989/1205). Both previous and current surgical factors were found to be significant contributors toward poorer clinical outcomes at 2 years. Having undergone previous arthrotomy (nonarthroscopic open approach) for ACL reconstruction compared with the 1-incision technique resulted in significantly poorer outcomes for the 2-year IKDC (P =.037; odds ratio [OR], 2.43; 95% CI, 1.05-5.88) and KOOS pain, sports/recreation, and quality of life (QOL) subscales (P ≤.05; OR range, 2.38-4.35; 95% CI, 1.03-10.00). The use of a metal interference screw for current femoral fixation resulted in significantly better outcomes for the 2-year KOOS symptoms, pain, and QOL subscales (P ≤.05; OR range, 1.70-1.96; 95% CI, 1.00-3.33) as well as WOMAC stiffness subscale (P =.041; OR, 1.75; 95% CI, 1.02-3.03). Not performing notchplasty at revision significantly improved 2-year outcomes for the IKDC (P =.013; OR, 1.47; 95% CI, 1.08-1.99), KOOS activities of daily living (ADL) and QOL subscales (P ≤.04; OR range, 1.40-1.41; 95% CI, 1.03-1.93), and WOMAC stiffness and ADL subscales (P ≤.04; OR range, 1.41-1.49; 95% CI, 1.03-2.05). Factors before revision ACL reconstruction that increased the risk of poorer clinical outcomes at 2 years included lower baseline outcome scores, a lower Marx activity score at the time of revision, a higher BMI, female sex, and a shorter time since the patient's last ACL reconstruction. Prior femoral fixation, prior femoral tunnel aperture position, and knee flexion angle at the time of revision graft fixation were not found to affect 2-year outcomes in this revision cohort. Conclusion: There are certain surgical variables that the physician can control at the time of revision ACL reconstruction that can modify clinical outcomes at 2 years. Whenever possible, opting for an anteromedial portal or transtibial surgical exposure, choosing a metal interference screw for femoral fixation, and not performing notchplasty are associated with significantly better 2-year clinical outcomes.
AB - Background: Revision anterior cruciate ligament (ACL) reconstruction has been documented to have worse outcomes compared with primary ACL reconstruction. Hypothesis: Certain factors under the control of the surgeon at the time of revision surgery can both negatively and positively affect outcomes. Study Design: Case-control study; Level of evidence, 3. Methods: Patients undergoing revision ACL reconstruction were identified and prospectively enrolled between 2006 and 2011. Data collected included baseline demographics, intraoperative surgical technique and joint disorders, and a series of validated patient-reported outcome instruments (International Knee Documentation Committee [IKDC] subjective form, Knee Injury and Osteoarthritis Outcome Score [KOOS], Western Ontario and McMaster Universities Osteoarthritis Index [WOMAC], and Marx activity rating scale) completed before surgery. Patients were followed up for 2 years and asked to complete an identical set of outcome instruments. Regression analysis was used to control for age, sex, body mass index (BMI), activity level, baseline outcome scores, revision number, time since last ACL reconstruction, and a variety of previous and current surgical variables to assess the surgical risk factors for clinical outcomes 2 years after revision ACL reconstruction. Results: A total of 1205 patients (697 male [58%]) met the inclusion criteria and were successfully enrolled. The median age was 26 years, and the median time since their last ACL reconstruction was 3.4 years. Two-year follow-up was obtained on 82% (989/1205). Both previous and current surgical factors were found to be significant contributors toward poorer clinical outcomes at 2 years. Having undergone previous arthrotomy (nonarthroscopic open approach) for ACL reconstruction compared with the 1-incision technique resulted in significantly poorer outcomes for the 2-year IKDC (P =.037; odds ratio [OR], 2.43; 95% CI, 1.05-5.88) and KOOS pain, sports/recreation, and quality of life (QOL) subscales (P ≤.05; OR range, 2.38-4.35; 95% CI, 1.03-10.00). The use of a metal interference screw for current femoral fixation resulted in significantly better outcomes for the 2-year KOOS symptoms, pain, and QOL subscales (P ≤.05; OR range, 1.70-1.96; 95% CI, 1.00-3.33) as well as WOMAC stiffness subscale (P =.041; OR, 1.75; 95% CI, 1.02-3.03). Not performing notchplasty at revision significantly improved 2-year outcomes for the IKDC (P =.013; OR, 1.47; 95% CI, 1.08-1.99), KOOS activities of daily living (ADL) and QOL subscales (P ≤.04; OR range, 1.40-1.41; 95% CI, 1.03-1.93), and WOMAC stiffness and ADL subscales (P ≤.04; OR range, 1.41-1.49; 95% CI, 1.03-2.05). Factors before revision ACL reconstruction that increased the risk of poorer clinical outcomes at 2 years included lower baseline outcome scores, a lower Marx activity score at the time of revision, a higher BMI, female sex, and a shorter time since the patient's last ACL reconstruction. Prior femoral fixation, prior femoral tunnel aperture position, and knee flexion angle at the time of revision graft fixation were not found to affect 2-year outcomes in this revision cohort. Conclusion: There are certain surgical variables that the physician can control at the time of revision ACL reconstruction that can modify clinical outcomes at 2 years. Whenever possible, opting for an anteromedial portal or transtibial surgical exposure, choosing a metal interference screw for femoral fixation, and not performing notchplasty are associated with significantly better 2-year clinical outcomes.
KW - ACL fixation
KW - anterior cruciate ligament
KW - outcomes
KW - revision ACL reconstruction
KW - surgical approach
KW - surgical factors
KW - tunnel position
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U2 - 10.1177/0363546517712952
DO - 10.1177/0363546517712952
M3 - Article
C2 - 28696164
AN - SCOPUS:85028728803
SN - 0363-5465
VL - 45
SP - 2586
EP - 2594
JO - American Journal of Sports Medicine
JF - American Journal of Sports Medicine
IS - 11
ER -