TY - JOUR
T1 - Strategies in the prevention of ventilator-associated pneumonia
AU - Maselli, Diego J.
AU - Restrepo, Marcos I.
N1 - Funding Information:
Dr Restrepo’s time is supported by the National Institute of Health and National Heart, Lung and Blood Institute (NIH/NHLBI) (award number K23HL096054). The content is solely the responsibility of the author and does not necessarily represent the official views of the NIH/NHLBI. The funding agencies had no role in the preparation, review, or approval of this presentation. The views expressed in this presentation are those of the author and do not necessarily represent the views of the Department of Veterans Affairs, nor the UTHSCSA.
PY - 2011/4
Y1 - 2011/4
N2 - Ventilator-associated pneumonia (VAP) remains a significant problem in the hospital setting, with very high morbidity, mortality, and cost. We performed an evidence-based review of the literature focusing on clinically relevant pharmacological and nonpharmacological interventions to prevent VAP. Owing to the importance of this condition the implementation of preventive measures is paramount in the care of mechanically ventilated patients. There is evidence that these measures decrease the incidence of VAP and improve outcomes in the intensive care unit. A multidisciplinary approach, continued education, and ventilator protocols ensure the implementation of these measures. Future research will continue to investigate cost/benefit relationships, antibiotic resistance, as well as newer technologies to prevent contamination and aspiration in mechanically ventilated patients.
AB - Ventilator-associated pneumonia (VAP) remains a significant problem in the hospital setting, with very high morbidity, mortality, and cost. We performed an evidence-based review of the literature focusing on clinically relevant pharmacological and nonpharmacological interventions to prevent VAP. Owing to the importance of this condition the implementation of preventive measures is paramount in the care of mechanically ventilated patients. There is evidence that these measures decrease the incidence of VAP and improve outcomes in the intensive care unit. A multidisciplinary approach, continued education, and ventilator protocols ensure the implementation of these measures. Future research will continue to investigate cost/benefit relationships, antibiotic resistance, as well as newer technologies to prevent contamination and aspiration in mechanically ventilated patients.
KW - ICU-related infections
KW - hospital acquired pneumonia
KW - preventive measures
KW - ventilator associated pneumonia
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U2 - 10.1177/1753465810395655
DO - 10.1177/1753465810395655
M3 - Review article
C2 - 21300737
AN - SCOPUS:79953328526
SN - 1753-4658
VL - 5
SP - 131
EP - 141
JO - Therapeutic Advances in Respiratory Disease
JF - Therapeutic Advances in Respiratory Disease
IS - 2
ER -