Resumen
Recently, Hou et al. shifted the research focus from the function of nuclear sirtuin (SIRT)6 to that of cytoplasmic SIRT6, which deacetylates and activates long-chain acyl-CoA synthase 5 (ACSL5). Their findings provide mechanistic insight into the role of cytoplasmic SIRT6 in fatty acid oxidation, acting as a therapeutic target for combating nonalcoholic fatty liver disease (NAFLD).
Idioma original | English (US) |
---|---|
Páginas (desde-hasta) | 801-803 |
Número de páginas | 3 |
Publicación | Trends in Endocrinology and Metabolism |
Volumen | 33 |
N.º | 12 |
DOI | |
Estado | Published - dic 2022 |
ASJC Scopus subject areas
- Endocrinology, Diabetes and Metabolism
- Endocrinology