Sirolimus plus sorafenib in treating HCC recurrence after liver transplantation: A case report

Yubao Wang, Kermit V. Speeg, William Kenneth Washburn, Glenn Halff

Producción científica: Articlerevisión exhaustiva

23 Citas (Scopus)

Resumen

A case of hepatocellular carcinoma (HCC) with pulmonary recurrence after liver transplantation for HCC is presented in this report. The patient showed disease progression on sorafenib therapy demonstrated by computed tomography scans as well as serial serum α-fetoprotein (AFP) elevation. After his immunosuppression therapy was successfully transitioned to sirolimus and a continuation of sorafenib, he achieved partial remission based on RECIST criteria and normalization of AFP. Mammalian target of rapamycin inhibitors including sirolimus alone or in conjunction with sorafenib may be useful in the treatment of post transplant HCC.

Idioma originalEnglish (US)
Páginas (desde-hasta)5518-5522
Número de páginas5
PublicaciónWorld Journal of Gastroenterology
Volumen16
N.º43
DOI
EstadoPublished - nov 21 2010

ASJC Scopus subject areas

  • Gastroenterology

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