Single muscle fiber discharges (Insertional activity, end-plate potentials, positive sharp waves, and fibrillation potentials): A unifying proposal

Resultado de la investigación: Review articlerevisión exhaustiva

22 Citas (Scopus)

Resumen

The exact origin and precise morphologic explanation of positive sharp waves (PSWs) are presently lacking. Observing normal needle electromyographic insertional activity reveals two types of waveforms: (1) biphasic negative/positive spikes, and (2) positive spikes followed by a small negative phase. In the end-plate region, it is possible to occasionally observe a biphasic end-plate spike transform into a monophasic positive end-plate waveform. It is postulated that this waveform is simply a form of intracellular recording for the biphasic end-plate spike or a form of extracellularly recorded but blocked single muscle fiber discharge. Similarly, the observed monophasic positive insertional activity may be an intracellularly recorded single muscle fiber discharge or a blocked extracellular discharge originating about the needle electrode. Applying this reasoning to PSWs suggests that they may also be an intracellular recording of a fibrillation potential, or needle-induced extracellular blocked local single muscle fiber discharge. This unifying concept is applied to various clinical situations purported to demonstrate "different" types of PSWs.

Idioma originalEnglish (US)
Páginas (desde-hasta)221-226
Número de páginas6
PublicaciónMuscle and Nerve
Volumen19
N.º2
DOI
EstadoPublished - feb. 1996

ASJC Scopus subject areas

  • Physiology
  • Clinical Neurology
  • Cellular and Molecular Neuroscience
  • Physiology (medical)

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