TY - JOUR
T1 - Severe Community-Acquired Pneumonia
AU - Restrepo, Marcos I.
AU - Anzueto, Antonio
N1 - Funding Information:
Dr. Restrepo is supported by a Department of Veteran Affairs Veterans Integrated Service Network 17 new faculty grant and a KL2 program sponsored by the National Institute of Health. The views expressed in this article are those of the authors and do not necessarily represent the views of the Department of Veterans Affairs. This material is the result of work supported with resources and the use of facilities at the South Texas Veterans Health Care System. The funding agencies had no role in conducting the study, or role in the preparation, review, or approval of the manuscript.
PY - 2009/9
Y1 - 2009/9
N2 - Community-acquired pneumonia (CAP) is the leading cause of death from infectious diseases in the United States. It accounts for 500,000 hospitalizations and 45,000 deaths each year, and it represents one of the most common causes of ICU admission. The mortality rate due to severe CAP has shown little improvement over the past few years, with rates as high as 58% when patients were admitted to the ICU. Significant interest has focused on the sickest patients who have pneumonia treated in the ICU, regarding identification of need for ICU admission and therapies directed to improve outcomes in patients who have severe CAP. This article reviews epidemiologic, microbiologic, therapeutic, preventive, and outcomes data in patients who have CAP in the ICU.
AB - Community-acquired pneumonia (CAP) is the leading cause of death from infectious diseases in the United States. It accounts for 500,000 hospitalizations and 45,000 deaths each year, and it represents one of the most common causes of ICU admission. The mortality rate due to severe CAP has shown little improvement over the past few years, with rates as high as 58% when patients were admitted to the ICU. Significant interest has focused on the sickest patients who have pneumonia treated in the ICU, regarding identification of need for ICU admission and therapies directed to improve outcomes in patients who have severe CAP. This article reviews epidemiologic, microbiologic, therapeutic, preventive, and outcomes data in patients who have CAP in the ICU.
KW - Community-acquired infections
KW - Intensive care unit
KW - Pneumonia
KW - Therapeutics
UR - http://www.scopus.com/inward/record.url?scp=68149167113&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=68149167113&partnerID=8YFLogxK
U2 - 10.1016/j.idc.2009.04.003
DO - 10.1016/j.idc.2009.04.003
M3 - Review article
C2 - 19665080
AN - SCOPUS:68149167113
SN - 0891-5520
VL - 23
SP - 503
EP - 520
JO - Infectious disease clinics of North America
JF - Infectious disease clinics of North America
IS - 3
ER -