Serological analysis of the repertoire of human cancer antigens and autoantigens

E. P. Koroleva; M. A. Lagarkova; S. V. Khlgatian; Yu V. Shebzukhov; A. A. Mescheryakov; M. R. Lichinitser; S. A. Nedospasov; D. V. Kuprash

doi:10.1023/B:MBIL.0000023733.36982.7d

Serological analysis of the repertoire of human cancer antigens and autoantigens

E. P. Koroleva, M. A. Lagarkova, S. V. Khlgatian, Yu V. Shebzukhov, A. A. Mescheryakov, M. R. Lichinitser, S. A. Nedospasov, D. V. Kuprash

Producción científica: Article › revisión exhaustiva

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Resumen

The spectrum of human antigens allows a monitoring of various pathological processes such as autoimmune disorders and tumorigenesis. Serological analysis of cDNA expression libraries (SEREX) is now used to search for new cancer-associated antigens, which are potential diagnostic markers or targets for immunotherapy of cancer. The results obtained for several solid tumors are reviewed. Groups of antigens detectable by SEREX, causes of immunogenicity of autoantigens, and prospective implication of antigens in diagnostics and monitoring of cancer are discussed.

Idioma original	English (US)
Páginas (desde-hasta)	191-195
Número de páginas	5
Publicación	Molecular Biology
Volumen	38
N.º	2
DOI	https://doi.org/10.1023/B:MBIL.0000023733.36982.7d
Estado	Published - mar 2004
Publicado de forma externa	Sí

ASJC Scopus subject areas

Biophysics
Structural Biology

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title = "Serological analysis of the repertoire of human cancer antigens and autoantigens",

abstract = "The spectrum of human antigens allows a monitoring of various pathological processes such as autoimmune disorders and tumorigenesis. Serological analysis of cDNA expression libraries (SEREX) is now used to search for new cancer-associated antigens, which are potential diagnostic markers or targets for immunotherapy of cancer. The results obtained for several solid tumors are reviewed. Groups of antigens detectable by SEREX, causes of immunogenicity of autoantigens, and prospective implication of antigens in diagnostics and monitoring of cancer are discussed.",

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T1 - Serological analysis of the repertoire of human cancer antigens and autoantigens

AU - Koroleva, E. P.

AU - Lagarkova, M. A.

AU - Khlgatian, S. V.

AU - Shebzukhov, Yu V.

AU - Mescheryakov, A. A.

AU - Lichinitser, M. R.

AU - Nedospasov, S. A.

AU - Kuprash, D. V.

PY - 2004/3

Y1 - 2004/3

N2 - The spectrum of human antigens allows a monitoring of various pathological processes such as autoimmune disorders and tumorigenesis. Serological analysis of cDNA expression libraries (SEREX) is now used to search for new cancer-associated antigens, which are potential diagnostic markers or targets for immunotherapy of cancer. The results obtained for several solid tumors are reviewed. Groups of antigens detectable by SEREX, causes of immunogenicity of autoantigens, and prospective implication of antigens in diagnostics and monitoring of cancer are discussed.

AB - The spectrum of human antigens allows a monitoring of various pathological processes such as autoimmune disorders and tumorigenesis. Serological analysis of cDNA expression libraries (SEREX) is now used to search for new cancer-associated antigens, which are potential diagnostic markers or targets for immunotherapy of cancer. The results obtained for several solid tumors are reviewed. Groups of antigens detectable by SEREX, causes of immunogenicity of autoantigens, and prospective implication of antigens in diagnostics and monitoring of cancer are discussed.

KW - Autoantigens

KW - Cancer immunodiagnostics

KW - Expression libraries

KW - cDNA

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Serological analysis of the repertoire of human cancer antigens and autoantigens

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