Serological analysis of the repertoire of human cancer antigens and autoantigens

E. P. Koroleva, M. A. Lagarkova, S. V. Khlgatian, Yu V. Shebzukhov, A. A. Mescheryakov, M. R. Lichinitser, S. A. Nedospasov, D. V. Kuprash

Resultado de la investigación: Articlerevisión exhaustiva

1 Cita (Scopus)

Resumen

The spectrum of human antigens allows a monitoring of various pathological processes such as autoimmune disorders and tumorigenesis. Serological analysis of cDNA expression libraries (SEREX) is now used to search for new cancer-associated antigens, which are potential diagnostic markers or targets for immunotherapy of cancer. The results obtained for several solid tumors are reviewed. Groups of antigens detectable by SEREX, causes of immunogenicity of autoantigens, and prospective implication of antigens in diagnostics and monitoring of cancer are discussed.

Idioma originalEnglish (US)
Páginas (desde-hasta)191-195
Número de páginas5
PublicaciónMolecular Biology
Volumen38
N.º2
DOI
EstadoPublished - mar. 1 2004
Publicado de forma externa

ASJC Scopus subject areas

  • Biophysics
  • Structural Biology

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