Seizure onset zone localization from many invasive EEG channels using directed functional connectivity

Pieter Van Mierlo, Ana Coito, Serge Vulliémoz, Octavian Lie

Producción científica: Conference contribution

3 Citas (Scopus)

Resumen

In this study we investigated how directed functional connectivity can be used to localize the seizure onset zone (SOZ) from ictal intracranial EEG (iEEG) recordings. First, simulations were conducted to investigate the performance of two directed functional connectivity measures, the Adaptive Directed Transfer Function (ADTF) and the Adaptive Partial Directed Coherence (APDC), in combinations with two graph measures, the out-degree and the shortest path, to localize the SOZ. Afterwards the method was applied to the seizure of an epileptic patient, recorded with 113-channel iEEG and localization was compared with the subsequent resection that rendered the patient seizure free. We found both in simulations and in the patient data that the ADTF combined with the out-degree and shortest path resulted in correct SOZ localization. We can conclude that ADTF combined with out-degree or shortest path are most optimal to localize the SOZ from a high number of iEEG channels.

Idioma originalEnglish (US)
Título de la publicación alojada2016 24th European Signal Processing Conference, EUSIPCO 2016
EditorialEuropean Signal Processing Conference, EUSIPCO
Páginas255-259
Número de páginas5
Volumen2016-November
ISBN (versión digital)9780992862657
DOI
EstadoPublished - nov 28 2016
Evento24th European Signal Processing Conference, EUSIPCO 2016 - Budapest, Hungary
Duración: ago 28 2016sept 2 2016

Other

Other24th European Signal Processing Conference, EUSIPCO 2016
País/TerritorioHungary
CiudadBudapest
Período8/28/169/2/16

ASJC Scopus subject areas

  • Signal Processing
  • Electrical and Electronic Engineering

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