TY - JOUR
T1 - Síndrome adyuvante por implante de prótesis mamarias de silicón (siliconosis) ¿una condición emergente?
AU - Karam, Emely
AU - Muci-Mendoza, Rafael
PY - 2011/4
Y1 - 2011/4
N2 - Silicone breast prosthesis has been associated with a variety of medical conditions or autoimmune diseases, which has coincidental relation with the implants insertion; it's loomed as a new and unknown pathology of the modern times. More than 87 % of symptomatic patients developed demyelination axonal neuropathy demonstrated by nerve and muscle biopsy; 22 % to 25 % have evidence of autoimmune thyroid disease. An a small group of patients (10.%-12.%) have primary central nervous system demyelination disease as, multiple sclerosis. The diagnosis of multiple sclerosis was corroborated by magnetic resonance imaging and cerebrospinal fluid analysis. Also, an other wide spectrum of immunological diseases have been observed, such as fibromyalgia, Hashimoto's thyroiditis, polymyositis, dermatomyositis, lupus erythematosus, rheumatoid arthritis, scleroderma, and the presence of autoantibodies. Finally, for symptomatic patients, an adjuvant syndrome of silicone breast prosthesis or implant is proposed as a unitary diagnosis. The authors presented two patients whom illustrated this entity.
AB - Silicone breast prosthesis has been associated with a variety of medical conditions or autoimmune diseases, which has coincidental relation with the implants insertion; it's loomed as a new and unknown pathology of the modern times. More than 87 % of symptomatic patients developed demyelination axonal neuropathy demonstrated by nerve and muscle biopsy; 22 % to 25 % have evidence of autoimmune thyroid disease. An a small group of patients (10.%-12.%) have primary central nervous system demyelination disease as, multiple sclerosis. The diagnosis of multiple sclerosis was corroborated by magnetic resonance imaging and cerebrospinal fluid analysis. Also, an other wide spectrum of immunological diseases have been observed, such as fibromyalgia, Hashimoto's thyroiditis, polymyositis, dermatomyositis, lupus erythematosus, rheumatoid arthritis, scleroderma, and the presence of autoantibodies. Finally, for symptomatic patients, an adjuvant syndrome of silicone breast prosthesis or implant is proposed as a unitary diagnosis. The authors presented two patients whom illustrated this entity.
KW - Autoantibodies
KW - Chronic inflammatory demyelinating polyneuropathy
KW - Dermatomyositis
KW - Fibromyalgia
KW - Hashimoto's thyroiditis
KW - Lupus erythematosus
KW - Multiple sclerosis-central demyelination
KW - Polymyositis
KW - Polyurethane
KW - Rheumatoid arthritis
KW - Scleroderma
KW - Silica
KW - Silicone
KW - Silicone breast implants
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M3 - Article
AN - SCOPUS:84874487892
SN - 0367-4762
VL - 119
SP - 154
EP - 161
JO - Gaceta Medica de Caracas
JF - Gaceta Medica de Caracas
IS - 2
ER -