TY - JOUR
T1 - Role of stent design and coatings on restenosis and thrombosis
AU - Hara, Hidehiko
AU - Nakamura, Masato
AU - Palmaz, Julio C.
AU - Schwartz, Robert S.
PY - 2006/6/3
Y1 - 2006/6/3
N2 - More than 15 years have passed since stent technology was introduced by Sigwart et al. [U. Sigwart, J. Puel, V. Mirkovitch, F. Joffe, et al. Intravascular stents to prevent occlusion and restenosis after transluminal angioplasty. N. Engl. J. Med. 316 (1987) 701-706.] among interventional cardiologists. Recently drug eluting stents have assumed dominance in the interventional world as positive trial results revealed their efficacy for preventing restenosis. Stent design, delivery-vehicle materials, and drug properties affect the function of these stents. Stainless steel stents with tubular and multicellular design have proven superior to coil or hybrid stent models. This chapter describes stents which have subtle influences of modular design, metal coverage, strut thickness, strut shape, surface smoothness, and coating materials like an alloy composition.
AB - More than 15 years have passed since stent technology was introduced by Sigwart et al. [U. Sigwart, J. Puel, V. Mirkovitch, F. Joffe, et al. Intravascular stents to prevent occlusion and restenosis after transluminal angioplasty. N. Engl. J. Med. 316 (1987) 701-706.] among interventional cardiologists. Recently drug eluting stents have assumed dominance in the interventional world as positive trial results revealed their efficacy for preventing restenosis. Stent design, delivery-vehicle materials, and drug properties affect the function of these stents. Stainless steel stents with tubular and multicellular design have proven superior to coil or hybrid stent models. This chapter describes stents which have subtle influences of modular design, metal coverage, strut thickness, strut shape, surface smoothness, and coating materials like an alloy composition.
KW - Drug eluting stent
KW - Restenosis
KW - Stent
KW - Stent design
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U2 - 10.1016/j.addr.2006.01.022
DO - 10.1016/j.addr.2006.01.022
M3 - Review article
C2 - 16650911
AN - SCOPUS:33744516940
SN - 0169-409X
VL - 58
SP - 377
EP - 386
JO - Advanced Drug Delivery Reviews
JF - Advanced Drug Delivery Reviews
IS - 3
ER -