Role of natural products in breast cancer related symptomology: Targeting chronic inflammation

Kristina Andrijauskaite, Michael J. Wargovich

Resultado de la investigación: Review articlerevisión exhaustiva

9 Citas (Scopus)


Breast cancer is the most common cancer in women worldwide. There have been many advancements in the treatment of breast cancer leading to an increased population of patients living with this disease. Accumulating evidence suggests that cancer diagnosis and aftermath experienced stress could not only affect the quality of life of cancer patients, but it could also influence their disease outcome. The magnitude of stress experienced by breast cancer patients is often compared to the post-traumatic stress disorder-like symptoms suggested to be mediated by the chronic inflammation including NF-κB, AKt, p53 and other inflammatory pathways. Here, we describe the symptomology of PTSD-like symptoms in breast cancer patients and argue that they may in fact be caused by or maintained through aspects of chronic inflammation mediated by the pro-inflammatory markers. Evidence exists that natural products that might attenuate or lessen the effects of chronic inflammation abound in the diet. We summarize some possible agents that might abate the genesis of symptoms experienced by breast cancer patients while mitigating the effect of inflammation.

Idioma originalEnglish (US)
Páginas (desde-hasta)370-378
Número de páginas9
PublicaciónSeminars in Cancer Biology
EstadoPublished - may 2022

ASJC Scopus subject areas

  • Cancer Research


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