In a model of pneumonia caused by murine Chlamydia trachomatis, depletion experiments with monoclonal antibody to gamma interferon (IFN-γ) made mice more susceptible. Repletion experiments giving exogenous recombinant murine IFN-γ were not consistently protective. IFN-γ may be necessary but not sufficient in host defense against the organism.
|Idioma original||English (US)|
|Número de páginas||3|
|Publicación||Infection and immunity|
|Estado||Published - 1988|
ASJC Scopus subject areas
- Infectious Diseases