Right hippocampus size is negatively correlated with leptin serum levels in bipolar disorder

Miréia Vianna-Sulzbach; Natalia P. Rocha; Antonio Lucio Teixeira; Eduarda D. Rosa; André A.S. Goldani; Marcia Kauer-Sant'Anna; Clarissa S. Gama

doi:10.1016/j.psychres.2015.09.040

Right hippocampus size is negatively correlated with leptin serum levels in bipolar disorder

Miréia Vianna-Sulzbach, Natalia P. Rocha, Antonio Lucio Teixeira, Eduarda D. Rosa, André A.S. Goldani, Marcia Kauer-Sant'Anna, Clarissa S. Gama

Producción científica: Article › revisión exhaustiva

5 Citas (Scopus)

Resumen

Obesity is more frequent in bipolar disorder. Adipokines are associated with depression and obesity via the inflammatory process. Twenty-six DSM-IV patients with BD and 39 controls were enrolled to assess the relationship between serum leptin and adiponectin with hippocampal volumes. Among patients, there was a significant negative correlation between right hippocampal volume and serum leptin levels. This result sum for the hypothesis of a pro-inflammatory state associated with BD and the prevalent co-morbid obesity.

Idioma original	English (US)
Páginas (desde-hasta)	719-721
Número de páginas	3
Publicación	Psychiatry Research
Volumen	230
N.º	2
DOI	https://doi.org/10.1016/j.psychres.2015.09.040
Estado	Published - dic 15 2015
Publicado de forma externa	Sí

ASJC Scopus subject areas

Psychiatry and Mental health
Biological Psychiatry

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10.1016/j.psychres.2015.09.040

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title = "Right hippocampus size is negatively correlated with leptin serum levels in bipolar disorder",

abstract = "Obesity is more frequent in bipolar disorder. Adipokines are associated with depression and obesity via the inflammatory process. Twenty-six DSM-IV patients with BD and 39 controls were enrolled to assess the relationship between serum leptin and adiponectin with hippocampal volumes. Among patients, there was a significant negative correlation between right hippocampal volume and serum leptin levels. This result sum for the hypothesis of a pro-inflammatory state associated with BD and the prevalent co-morbid obesity.",

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doi = "10.1016/j.psychres.2015.09.040",

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T1 - Right hippocampus size is negatively correlated with leptin serum levels in bipolar disorder

AU - Vianna-Sulzbach, Miréia

AU - Rocha, Natalia P.

AU - Teixeira, Antonio Lucio

AU - Rosa, Eduarda D.

AU - Goldani, André A.S.

AU - Kauer-Sant'Anna, Marcia

AU - Gama, Clarissa S.

PY - 2015/12/15

Y1 - 2015/12/15

N2 - Obesity is more frequent in bipolar disorder. Adipokines are associated with depression and obesity via the inflammatory process. Twenty-six DSM-IV patients with BD and 39 controls were enrolled to assess the relationship between serum leptin and adiponectin with hippocampal volumes. Among patients, there was a significant negative correlation between right hippocampal volume and serum leptin levels. This result sum for the hypothesis of a pro-inflammatory state associated with BD and the prevalent co-morbid obesity.

AB - Obesity is more frequent in bipolar disorder. Adipokines are associated with depression and obesity via the inflammatory process. Twenty-six DSM-IV patients with BD and 39 controls were enrolled to assess the relationship between serum leptin and adiponectin with hippocampal volumes. Among patients, there was a significant negative correlation between right hippocampal volume and serum leptin levels. This result sum for the hypothesis of a pro-inflammatory state associated with BD and the prevalent co-morbid obesity.

KW - Adipokines

KW - Bipolar Disorder

KW - Hippocampal volume

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EP - 721

JO - Psychiatry Research

JF - Psychiatry Research

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ER -

Right hippocampus size is negatively correlated with leptin serum levels in bipolar disorder

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