Right atrial botryoid rhabdomyosarcoma in an adult patient with recurrent pleomorphic rhabdomyosarcomas following doxorubicin therapy

We describe a case of a 37-year-old Hispanic woman who presented with a right atrial botryoid rhabdomyosarcoma 2 years after doxorubicin therapy for a recurrent pleomorphic rhabdomyosarcoma of the chest wall. Although this may be a second primary, it most likely represents a cardiac metastasis with maturation of chemotherapy-resistant tumor cells.