Rhabdomyosarcoma. From the laboratory to the clinic

P. J. Houghton, D. N. Shapiro, J. A. Houghton

Producción científica: Articlerevisión exhaustiva

12 Citas (Scopus)


The prospect of identifying and developing new agents for treatment of rhabdomyosarcomas is discussed in the light of current prognosis for children with advanced stage disease. Preliminary attempts to identify tumor-specific agents using in vitro cell culture show potential promise, but as yet remain unproven. The more complex system of identifying therapeutically active agents using human tumor xenografts has demonstrated usefulness. The potential problems associated with this system are discussed.

Idioma originalEnglish (US)
Páginas (desde-hasta)349-364
Número de páginas16
PublicaciónPediatric Clinics of North America
EstadoPublished - 1991
Publicado de forma externa

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health


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