@article{e34a39fb89c44962993f1bf19894d91c,
title = "Rhabdomyosarcoma. From the laboratory to the clinic",
abstract = "The prospect of identifying and developing new agents for treatment of rhabdomyosarcomas is discussed in the light of current prognosis for children with advanced stage disease. Preliminary attempts to identify tumor-specific agents using in vitro cell culture show potential promise, but as yet remain unproven. The more complex system of identifying therapeutically active agents using human tumor xenografts has demonstrated usefulness. The potential problems associated with this system are discussed.",
author = "Houghton, {P. J.} and Shapiro, {D. N.} and Houghton, {J. A.}",
note = "Funding Information: *Member, Laboratories for Developmental Therapeutics. Department of Biochemical and Clinical Pharmacology, St. Jude Children's Research Hospital, Memphis, Tennessee tAssistant Member, Department of Hematology-Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee; and Professor, Department of Pediatrics, University of Tennessee Center for Health Sciences, Memphis, Tennessee *Member, Laboratories for Developmental Therapeutics, Department of Biochemical and Clinical Pharmacology, St. Jude Children's Research Hospital, Memphis, Tennessee This work was supported in part by American Cancer Society award CH-423, and PHS grants CA 23099 and CA 21765 from the National Cancer Institute and by American Lebanese Syrian Associated Charities (ALSAC).",
year = "1991",
doi = "10.1016/S0031-3955(16)38081-6",
language = "English (US)",
volume = "38",
pages = "349--364",
journal = "Pediatric Clinics of North America",
issn = "0031-3955",
publisher = "W.B. Saunders",
number = "2",
}