TY - JOUR
T1 - Revisiting the neuropsychiatry of Huntington’s disease
AU - Teixeira, Antonio Lucio
AU - De Souza, Leonardo Cruz
AU - Rocha, Natalia Pessoa
AU - Furr-Stimming, Erin
AU - Lauterbach, Edward C.
N1 - Publisher Copyright:
© 2016, Academia Brasileira de Neurologia. All rights reserved.
PY - 2016/10/1
Y1 - 2016/10/1
N2 - Huntington’s disease (HD) is an autosomal dominant neurodegenerative disease classified under the choreas. Besides motor symptoms, HD is marked by cognitive and behavioral symptoms, impacting patients’ functional capacity. The progression of cognitive impairment and neuropsychiatric symptoms occur in parallel with neurodegeneration. The nature of these symptoms is very dynamic, and the major clinical challenges include executive dysfunction, apathy, depression and irritability. Herein, we provide a focused updated review on the cognitive and psychiatric features of HD.
AB - Huntington’s disease (HD) is an autosomal dominant neurodegenerative disease classified under the choreas. Besides motor symptoms, HD is marked by cognitive and behavioral symptoms, impacting patients’ functional capacity. The progression of cognitive impairment and neuropsychiatric symptoms occur in parallel with neurodegeneration. The nature of these symptoms is very dynamic, and the major clinical challenges include executive dysfunction, apathy, depression and irritability. Herein, we provide a focused updated review on the cognitive and psychiatric features of HD.
KW - Behavior
KW - Cognition
KW - Huntington’s disease
KW - Neuropsychiatry
UR - https://www.scopus.com/pages/publications/85007524248
UR - https://www.scopus.com/inward/citedby.url?scp=85007524248&partnerID=8YFLogxK
U2 - 10.1590/s1980-5764-2016dn1004002
DO - 10.1590/s1980-5764-2016dn1004002
M3 - Article
AN - SCOPUS:85007524248
SN - 1980-5764
VL - 10
SP - 261
EP - 266
JO - Dementia e Neuropsychologia
JF - Dementia e Neuropsychologia
IS - 4
ER -