Recoverin and rhodopsin kinase

Producción científica: Articlerevisión exhaustiva

15 Citas (Scopus)

Resumen

The majority of proteins involved in vertebrate phototransduction are expressed specifically in photoreceptors. Recoverin and rhodopsin kinase are expressed primarily in retinal photoreceptors and they interact with each other in a Ca2+-dependent manner. This Ca2+-dependent interaction has been studied extensively in vitro. Experiments utilizing animal models and electrophysiological approaches have started to provide important insight regarding its in vivo function. Recoverin can be viewed as a negative regulator of rhodopsin kinase in vertebrate phototransduction. This interaction imparts a negative feedback loop at the receptor level and may play an important role in light adaptation and in recovery.

Idioma originalEnglish (US)
Páginas (desde-hasta)101-107
Número de páginas7
PublicaciónAdvances in experimental medicine and biology
Volumen514
DOI
EstadoPublished - 2002
Publicado de forma externa

ASJC Scopus subject areas

  • General Biochemistry, Genetics and Molecular Biology

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