Reactive non-sexually related acute genital ulcers associated with COVID-19

Jill M. Krapf, Rachel K. Casey, Andrew T. Goldstein

Resultado de la investigación: Articlerevisión exhaustiva

6 Citas (Scopus)


Acute genital ulcers (AGU), known as Lipschu¨tz ulcers, are painful vulvar ulcers typically affecting non-sexually active girls and women. AGU have been associated with viral infections, namely, Epstein-Barr virus (EBV). Here, we describe a case of AGU in the setting of SARS-CoV-2 in a non-sexually active adolescent girl hospitalised for pain control and urinary retention, who failed a course of oral corticosteroids and then improved with colchicine. Testing for herpes simplex virus, EBV and Behcet's syndrome were all negative. Testing for SARS-CoV-2 was positive. COVID-19 increases cytokines such as tumour necrosis factor alpha, which has been shown to affect endothelial cell adhesion and neutrophil chemotaxis, leading to aphthosis.

Idioma originalEnglish (US)
Número de artículoe242653
PublicaciónBMJ case reports
EstadoPublished - may. 5 2021
Publicado de forma externa

ASJC Scopus subject areas

  • Medicine(all)


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