Rationale and study design of a randomized clinical trial of metformin to prevent frailty in older adults with prediabetes

Medicine and Dentistry

• Frailty 100%
• Impaired Glucose Tolerance 70%
• Glycon 70%
• Older Adult 50%
• Oral Glucose Tolerance Test 30%
• Diabetes 20%
• Insulin Sensitivity 20%
• Placebo 20%
• Aging 10%
• Serositis 10%
• Health Outcomes 10%
• Depression 10%
• Dementia 10%
• Insulin 10%
• Skeletal Muscle 10%
• Silo-Filler's Disease 10%
• Cardiovascular Disease 10%
• Screening 10%
• Insulin Resistance 10%
• Glucose Tolerance 10%
• Randomized Clinical Trial 10%
• Safety Assessment 10%
• Therapeutic Agent 10%
• Neurologic Disease 10%
• Insulin Signaling 10%
• Physical Performance 10%
• Absorptiometry 10%
• Myositis 10%
• Drug 10%
• Chemotherapeutic Agent 10%
• Healthy Aging 10%
• Geriatric Syndrome 10%
• Therapeutic Procedure 10%
• Assessment 10%
• Adult 10%
• Patient 10%
• Anti-Inflammatory Drug 10%
• Study Design 10%
• Cancer 10%
• Clinical Trial 10%
• Muscle Tissue 10%