Rapid identification of Cryptococcus neoformans and Cryptococcus gattii by matrix-assisted laser desorption ionization-time of flight mass spectrometry

Lisa R. McTaggart, Eric Lei, Susan E. Richardson, Linda Hoang, Annette Fothergill, Sean X. Zhang

Resultado de la investigación: Articlerevisión exhaustiva

80 Citas (Scopus)

Resumen

Compared to DNA sequence analysis, matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) correctly identified 100% of Cryptococcus species, distinguishing the notable pathogens Cryptococcus neoformans and C. gattii. Identification was greatly enhanced by supplementing a commercial spectral library with additional entries to account for subspecies variability.

Idioma originalEnglish (US)
Páginas (desde-hasta)3050-3053
Número de páginas4
PublicaciónJournal of clinical microbiology
Volumen49
N.º8
DOI
EstadoPublished - ago. 2011

ASJC Scopus subject areas

  • Microbiology (medical)

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