Rapamycin, anti-aging, and avoiding the fate of Tithonus

Arlan Richardson

Resultado de la investigación: Review articlerevisión exhaustiva

29 Citas (Scopus)


The discovery that rapamycin increased the lifespan of mice was recognized by Science as one of the top 10 scientific breakthroughs of 2009. In addition to increasing lifespan, Neff and colleagues show that while rapamycin improves several functions/pathologies that change with age, it has little effect on the majority of the physiological and structural parameters they evaluated. What do these data tell us about the ability of rapamycin to delay aging and improve quality of life, i.e., prevent the fate of Tithonu.

Idioma originalEnglish (US)
Páginas (desde-hasta)3204-3206
Número de páginas3
PublicaciónJournal of Clinical Investigation
EstadoPublished - ago 1 2013

ASJC Scopus subject areas

  • Medicine(all)


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