Primary neoplastic transformation in vivo of xenogeneic skin grafts on nude mice

John W. Kreider; Gerald L. Bartlett; Francis E. Sharkey

Primary neoplastic transformation in vivo of xenogeneic skin grafts on nude mice

John W. Kreider
, Gerald L. Bartlett
, Francis E. Sharkey

Producción científica: Article › revisión exhaustiva

Resumen

Rabbit skin was infected with Shope papilloma virus and grafted orthotopically to nude mice. Typical Shope rabbit papillomas developed in most of the grafts, but similarly treated nude mouse skin grafts were not altered. These results demonstrated that xenogeneic tissues retained susceptibility to oncogenic agents after transplantation to nude mice. The results also implied that it should be feasible to study carcinogenesis of human tissues in this system.

Idioma original	English (US)
Páginas (desde-hasta)	273-276
Número de páginas	4
Publicación	Cancer Research
Volumen	39
N.º	1
Estado	Published - ene 1 1979
Publicado de forma externa	Sí

ASJC Scopus subject areas

Oncology
Cancer Research

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title = "Primary neoplastic transformation in vivo of xenogeneic skin grafts on nude mice",

abstract = "Rabbit skin was infected with Shope papilloma virus and grafted orthotopically to nude mice. Typical Shope rabbit papillomas developed in most of the grafts, but similarly treated nude mouse skin grafts were not altered. These results demonstrated that xenogeneic tissues retained susceptibility to oncogenic agents after transplantation to nude mice. The results also implied that it should be feasible to study carcinogenesis of human tissues in this system.",

author = "Kreider, \{John W.\} and Bartlett, \{Gerald L.\} and Sharkey, \{Francis E.\}",

year = "1979",

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language = "English (US)",

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pages = "273--276",

journal = "Cancer Research",

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T1 - Primary neoplastic transformation in vivo of xenogeneic skin grafts on nude mice

AU - Kreider, John W.

AU - Bartlett, Gerald L.

AU - Sharkey, Francis E.

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Y1 - 1979/1/1

N2 - Rabbit skin was infected with Shope papilloma virus and grafted orthotopically to nude mice. Typical Shope rabbit papillomas developed in most of the grafts, but similarly treated nude mouse skin grafts were not altered. These results demonstrated that xenogeneic tissues retained susceptibility to oncogenic agents after transplantation to nude mice. The results also implied that it should be feasible to study carcinogenesis of human tissues in this system.

AB - Rabbit skin was infected with Shope papilloma virus and grafted orthotopically to nude mice. Typical Shope rabbit papillomas developed in most of the grafts, but similarly treated nude mouse skin grafts were not altered. These results demonstrated that xenogeneic tissues retained susceptibility to oncogenic agents after transplantation to nude mice. The results also implied that it should be feasible to study carcinogenesis of human tissues in this system.

UR - https://www.scopus.com/pages/publications/0018412457

UR - https://www.scopus.com/pages/publications/0018412457#tab=citedBy

M3 - Article

C2 - 367580

AN - SCOPUS:0018412457

SN - 0008-5472

VL - 39

SP - 273

EP - 276

JO - Cancer Research

JF - Cancer Research

IS - 1

ER -

Primary neoplastic transformation in vivo of xenogeneic skin grafts on nude mice

Resumen

ASJC Scopus subject areas

Otros archivos y enlaces

Huella

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