Predictors of outcome in phaeochromocytomas and paragangliomas

Patricia Dahia, Marlo Nicolas

Producción científica: Review articlerevisión exhaustiva

5 Citas (Scopus)

Resumen

Phaeochromocytomas and paragangliomas (PPGLs) are catecholamine-secreting neuroendocrine tumours characterised by high rates of heritability and genetic heterogeneity. Despite advances in the genetic diagnosis and improved understanding of the molecular aberrations underlying these tumours, predictive markers of malignancy remain scarce, limiting the outlook of patients with metastatic PPGL. The identification of robust predictive markers remains the most pressing challenge in PPGL management, so that the potential of targeted therapy to impact patient care can be fully realised.

Idioma originalEnglish (US)
Número de artículo2160
PublicaciónF1000Research
Volumen6
DOI
EstadoPublished - 2017

ASJC Scopus subject areas

  • General Biochemistry, Genetics and Molecular Biology
  • General Immunology and Microbiology
  • General Pharmacology, Toxicology and Pharmaceutics

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