Resumen
Background: We aimed to establish the prognostic value of 18F-fluoro-deoxy-glucose positron emission/CT (18F-FDG PET/CT) and diffusion-weighted (DW) MRI in determining overall survival (OS), progression-free survival (PFS), and distant metastasis-free survival (DMFS) of sinonasal malignancies. Methods: Sixty-eight patients with sinonasal cancer who underwent both pretreatment 18F-FDG PET/CT scan and head-neck MRI from January 2009 through August 2017 were retrospectively reviewed. Kaplan-Meier survival analysis of 18F-FDG PET/CT and DW-MRI parameters were performed for OS, PFS, and DMFS. Results: Cox regression analysis determined that all the quantitative 18F-FDG PET/CT and DW-MRI parameters were independently correlated with PFS, DMFS, and OS (P <.05). After controlling for imaging variables, perineural invasion (P =.02) and ill-defined margin (P =.02) were found to be significantly correlated with shorter OS; while the perineural invasion was significantly correlated with shorter PFS (P =.02). Conclusions: The pretreatment DW-MRI and 18F-FDG PET/CT parameters could be substantial surrogate markers for sinonasal malignancies.
Idioma original | English (US) |
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Páginas (desde-hasta) | 3080-3089 |
Número de páginas | 10 |
Publicación | Head and Neck |
Volumen | 41 |
N.º | 9 |
DOI | |
Estado | Published - sept 2019 |
Publicado de forma externa | Sí |
ASJC Scopus subject areas
- Otorhinolaryngology