Resumen
We investigated the effect of the selective D1 dopamine antagonist, SCH23390, on the establishment of a pipradrol-conditioned place preference (CPP). Among various doses of pipradrol (6.25-75.0 mg/kg, SC), a CPP was established at 25.0 mg/kg. SCH23390 (0.16 mg/kg, IP) blocked establishment of a CPP by this dose of pipradrol. The results suggest that pipradrol produces a rewarding effect and that this effect may involve activation of D1dopamine receptors.
| Idioma original | English (US) |
|---|---|
| Páginas (desde-hasta) | 377-380 |
| Número de páginas | 4 |
| Publicación | Pharmacology, Biochemistry and Behavior |
| Volumen | 43 |
| N.º | 2 |
| DOI | |
| Estado | Published - oct 1992 |
| Publicado de forma externa | Sí |
ASJC Scopus subject areas
- Biological Psychiatry
- Biochemistry
- Behavioral Neuroscience
- Clinical Biochemistry
- Toxicology
- Pharmacology