PI3-kinase signaling pathway mediates changes in the structural and functional state of leukocyte membranes under type 1 diabetes mellitus

Mykola Zdioruk; Iryna Brodyak; Viktor Drel; Nataliya Sybirna

PI3-kinase signaling pathway mediates changes in the structural and functional state of leukocyte membranes under type 1 diabetes mellitus

Mykola Zdioruk, Iryna Brodyak, Viktor Drel, Nataliya Sybirna

Resultado de la investigación: Article › revisión exhaustiva

Resumen

The research reveals the lectin-induced leukocyte aggregation abilities in healthy donors and type 1 diabetics. It is shown that PI-3'-kinase participates in signal pathways mediating changes in molecular mechanisms responsible for aggregation and adhesion of leukocytic series blood cells. The obtained results may be used in the development of a test system for diabetic diagnosis.

Idioma original	English (US)
Páginas (desde-hasta)	221-225
Número de páginas	5
Publicación	Annales Universitatis Mariae Curie-Sklodowska, Sectio DDD: Pharmacia
Volumen	23
N.º	2
Estado	Published - 2010
Publicado de forma externa	Sí

ASJC Scopus subject areas

Biochemistry
Molecular Biology
Pharmacology

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abstract = "The research reveals the lectin-induced leukocyte aggregation abilities in healthy donors and type 1 diabetics. It is shown that PI-3'-kinase participates in signal pathways mediating changes in molecular mechanisms responsible for aggregation and adhesion of leukocytic series blood cells. The obtained results may be used in the development of a test system for diabetic diagnosis.",

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AU - Zdioruk, Mykola

AU - Brodyak, Iryna

AU - Drel, Viktor

AU - Sybirna, Nataliya

PY - 2010

Y1 - 2010

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AB - The research reveals the lectin-induced leukocyte aggregation abilities in healthy donors and type 1 diabetics. It is shown that PI-3'-kinase participates in signal pathways mediating changes in molecular mechanisms responsible for aggregation and adhesion of leukocytic series blood cells. The obtained results may be used in the development of a test system for diabetic diagnosis.

KW - Aggregation activity

KW - Lectins

KW - Leukocyte

KW - Type 1 diabetes mellitus

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PI3-kinase signaling pathway mediates changes in the structural and functional state of leukocyte membranes under type 1 diabetes mellitus

Resumen

ASJC Scopus subject areas

Otros archivos y enlaces

Huella

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