PI3-kinase signaling pathway mediates changes in the structural and functional state of leukocyte membranes under type 1 diabetes mellitus

Mykola Zdioruk, Iryna Brodyak, Viktor Drel, Nataliya Sybirna

Producción científica: Articlerevisión exhaustiva

1 Cita (Scopus)

Resumen

The research reveals the lectin-induced leukocyte aggregation abilities in healthy donors and type 1 diabetics. It is shown that PI-3'-kinase participates in signal pathways mediating changes in molecular mechanisms responsible for aggregation and adhesion of leukocytic series blood cells. The obtained results may be used in the development of a test system for diabetic diagnosis.

Idioma originalEnglish (US)
Páginas (desde-hasta)221-225
Número de páginas5
PublicaciónAnnales Universitatis Mariae Curie-Sklodowska, Sectio DDD: Pharmacia
Volumen23
N.º2
EstadoPublished - 2010
Publicado de forma externa

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Pharmacology

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