Photoswitchable particles for on-demand degradation and triggered release

Tae Hong Park; Thomas W. Eyster; Joshua M. Lumley; Sangyeul Hwang; Kyung Jin Lee; Asish Misra; Sahar Rahmani; Joerg Lahann

doi:10.1002/smll.201201921

Photoswitchable particles for on-demand degradation and triggered release

Tae Hong Park, Thomas W. Eyster, Joshua M. Lumley, Sangyeul Hwang, Kyung Jin Lee, Asish Misra, Sahar Rahmani, Joerg Lahann

Producción científica: Article › revisión exhaustiva

14 Citas (Scopus)

Resumen

On-demand degradable polymer particles are fabricated via electrospraying of a solution of acetal-protected dextran that further includes 2-(4-methoxystyryl)-4,6-bis(trichloromethyl)-1,3,5-triazine as a photoacid generator. The illumination of UV light gives rise to photoacid and activates the catalytic deprotection of hydroxyl groups of dextran, leading to controlled dissolution of the microparticles in water.

Idioma original	English (US)
Páginas (desde-hasta)	3051-3057
Número de páginas	7
Publicación	Small
Volumen	9
N.º	18
DOI	https://doi.org/10.1002/smll.201201921
Estado	Published - sept 23 2013
Publicado de forma externa	Sí

ASJC Scopus subject areas

Biotechnology
General Chemistry
Biomaterials
General Materials Science
Engineering (miscellaneous)

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title = "Photoswitchable particles for on-demand degradation and triggered release",

abstract = "On-demand degradable polymer particles are fabricated via electrospraying of a solution of acetal-protected dextran that further includes 2-(4-methoxystyryl)-4,6-bis(trichloromethyl)-1,3,5-triazine as a photoacid generator. The illumination of UV light gives rise to photoacid and activates the catalytic deprotection of hydroxyl groups of dextran, leading to controlled dissolution of the microparticles in water.",

keywords = "biopolymers, drug delivery, electrospinning, nanoparticles, photoswitching",

author = "Park, {Tae Hong} and Eyster, {Thomas W.} and Lumley, {Joshua M.} and Sangyeul Hwang and Lee, {Kyung Jin} and Asish Misra and Sahar Rahmani and Joerg Lahann",

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AU - Park, Tae Hong

AU - Eyster, Thomas W.

AU - Lumley, Joshua M.

AU - Hwang, Sangyeul

AU - Lee, Kyung Jin

AU - Misra, Asish

AU - Rahmani, Sahar

AU - Lahann, Joerg

PY - 2013/9/23

Y1 - 2013/9/23

N2 - On-demand degradable polymer particles are fabricated via electrospraying of a solution of acetal-protected dextran that further includes 2-(4-methoxystyryl)-4,6-bis(trichloromethyl)-1,3,5-triazine as a photoacid generator. The illumination of UV light gives rise to photoacid and activates the catalytic deprotection of hydroxyl groups of dextran, leading to controlled dissolution of the microparticles in water.

AB - On-demand degradable polymer particles are fabricated via electrospraying of a solution of acetal-protected dextran that further includes 2-(4-methoxystyryl)-4,6-bis(trichloromethyl)-1,3,5-triazine as a photoacid generator. The illumination of UV light gives rise to photoacid and activates the catalytic deprotection of hydroxyl groups of dextran, leading to controlled dissolution of the microparticles in water.

KW - biopolymers

KW - drug delivery

KW - electrospinning

KW - nanoparticles

KW - photoswitching

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JO - Small

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ER -

Photoswitchable particles for on-demand degradation and triggered release

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ASJC Scopus subject areas

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