Pathways mediating low shear stress-induced vascular endothelial gene activation

Eugene A. Sprague; Sumathy Mohan; Lisa Ballou; Robert M. Nerem

Pathways mediating low shear stress-induced vascular endothelial gene activation

Eugene A. Sprague, Sumathy Mohan, Lisa Ballou, Robert M. Nerem

Producción científica: Conference contribution

Resumen

An account is given on new data indicating that low shear induced MCP-1 and VCAM-1 gene activation may involve interaction of multiple signal transduction pathways, including the NF-kB and mitogen-activated protein kinase (MAPK) systems. The data indicate that NF-kB plays a key role in the endothelial response to chronic LS flow conditions.

Idioma original	English (US)
Título de la publicación alojada	American Society of Mechanical Engineers, Bioengineering Division (Publication) BED
Editorial	ASME
Páginas	655-656
Número de páginas	2
Volumen	42
ISBN (versión impresa)	0791816117
Estado	Published - 1999
Evento	1999 Bioengineering Conference - Big Sky, MT, USA Duración: jun 16 1999 → jun 20 1999

Other

Other	1999 Bioengineering Conference
Ciudad	Big Sky, MT, USA
Período	6/16/99 → 6/20/99

ASJC Scopus subject areas

General Engineering

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title = "Pathways mediating low shear stress-induced vascular endothelial gene activation",

abstract = "An account is given on new data indicating that low shear induced MCP-1 and VCAM-1 gene activation may involve interaction of multiple signal transduction pathways, including the NF-kB and mitogen-activated protein kinase (MAPK) systems. The data indicate that NF-kB plays a key role in the endothelial response to chronic LS flow conditions.",

author = "Sprague, {Eugene A.} and Sumathy Mohan and Lisa Ballou and Nerem, {Robert M.}",

year = "1999",

language = "English (US)",

isbn = "0791816117",

volume = "42",

pages = "655--656",

booktitle = "American Society of Mechanical Engineers, Bioengineering Division (Publication) BED",

publisher = "ASME",

note = "1999 Bioengineering Conference ; Conference date: 16-06-1999 Through 20-06-1999",

}

TY - GEN

T1 - Pathways mediating low shear stress-induced vascular endothelial gene activation

AU - Sprague, Eugene A.

AU - Mohan, Sumathy

AU - Ballou, Lisa

AU - Nerem, Robert M.

PY - 1999

Y1 - 1999

N2 - An account is given on new data indicating that low shear induced MCP-1 and VCAM-1 gene activation may involve interaction of multiple signal transduction pathways, including the NF-kB and mitogen-activated protein kinase (MAPK) systems. The data indicate that NF-kB plays a key role in the endothelial response to chronic LS flow conditions.

AB - An account is given on new data indicating that low shear induced MCP-1 and VCAM-1 gene activation may involve interaction of multiple signal transduction pathways, including the NF-kB and mitogen-activated protein kinase (MAPK) systems. The data indicate that NF-kB plays a key role in the endothelial response to chronic LS flow conditions.

UR - http://www.scopus.com/inward/record.url?scp=0033298690&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0033298690&partnerID=8YFLogxK

M3 - Conference contribution

AN - SCOPUS:0033298690

SN - 0791816117

VL - 42

SP - 655

EP - 656

BT - American Society of Mechanical Engineers, Bioengineering Division (Publication) BED

PB - ASME

T2 - 1999 Bioengineering Conference

Y2 - 16 June 1999 through 20 June 1999

ER -

Pathways mediating low shear stress-induced vascular endothelial gene activation

Resumen

Other

ASJC Scopus subject areas

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Huella

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