Parasite-parasite interaction of Salmonella typhimurium and Schistosoma

P. T. LoVerde, C. Amento, G. I. Higashi

Resultado de la investigación: Articlerevisión exhaustiva

29 Citas (Scopus)

Resumen

The parasite-parasite interaction of Salmonella and Schistosoma was studied. Salmonella typhimurium LT2 was found to associate in vitro with three human species of Schistosoma: Schistosoma mansoni, Schistosoma haematobium, and Schistosoma japonicum. Genetic mutants of S. typhimurium were allowed to interact with ligatured and unligatured worms of S. mansoni in vitro. These studies were undertaken to elucide the mechanism(s) of the parasite-parasite interaction of Salmonella on the surface of Schistosoma. The galE and fla mutants showed 100% association with male schistosomes, but a reduced interaction with female worms. The rough A and pili mutants showed a significant reduction in the ability to associate with both male and female S. mansoni. Observations with the scanning electron microscope revealed that pili function in adhesion of Salmonella to the surface tegument of S. mansoni haematobium. The association of Salmonella and Schistosoma may contribute to persistence of salmonella infection.

Idioma originalEnglish (US)
Páginas (desde-hasta)177-185
Número de páginas9
PublicaciónJournal of Infectious Diseases
Volumen141
N.º2
DOI
EstadoPublished - ene. 1 1980
Publicado de forma externa

ASJC Scopus subject areas

  • Immunology and Allergy
  • Infectious Diseases

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