Packaging of non-coding RNAs into herpesvirus virions: Comparisons to coding RNAs

Melanie A. Amen, Anthony Griffiths

Resultado de la investigación: Articlerevisión exhaustiva

8 Citas (Scopus)

Resumen

The herpesviruses are a family of large DNA viruses capable of establishing lifelong infections. Recent reports have shown that herpesviruses package non-coding RNA into virions; this follows earlier observations showing that coding RNAs are detected in virions. Packaging RNAs allows for their function immediately after virus entry and in the absence of de novo transcription. Despite the collective understanding that RNAs are packaged into herpesvirus virions, many questions remain. This review will highlight what is known regarding packaged coding and non-coding RNAs and discuss their potential impact to virus biology.

Idioma originalEnglish (US)
Número de artículoArticle 81
PublicaciónFrontiers in Genetics
Volumen2
N.ºNOV
DOI
EstadoPublished - 2011
Publicado de forma externa

ASJC Scopus subject areas

  • Molecular Medicine
  • Genetics
  • Genetics(clinical)

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