TY - JOUR
T1 - O papel das quimiocinas nas uveítes
AU - Gonçalves, Roberto Martins
AU - Teixeira, Antônio Lúcio
AU - Campos, Wesley Ribeiro
AU - Oréfice, Fernando
PY - 2007
Y1 - 2007
N2 - Inflammation is part of the physiological process that aims at repairing the damage produced by different causes such as infection, trauma, and autoimmune disease. However, when this physiological process is not regulated, it can contribute to the increase in tissue damage. Chemokines and their receptors are major factors involved in the process of cell migration into inflamed tissues. In the ocular diseases, mainly in uveitis, such proteins have been identified as important mediators of the inflammation process. This review discusses the role of chemokines in several ocular diseases, with emphasis on the uveitic process.
AB - Inflammation is part of the physiological process that aims at repairing the damage produced by different causes such as infection, trauma, and autoimmune disease. However, when this physiological process is not regulated, it can contribute to the increase in tissue damage. Chemokines and their receptors are major factors involved in the process of cell migration into inflamed tissues. In the ocular diseases, mainly in uveitis, such proteins have been identified as important mediators of the inflammation process. This review discusses the role of chemokines in several ocular diseases, with emphasis on the uveitic process.
KW - Chemokines
KW - Inflammation
KW - Review
KW - Uveal diseases
KW - Uveitis
UR - http://www.scopus.com/inward/record.url?scp=34249951244&partnerID=8YFLogxK
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U2 - 10.1590/s0004-27492007000200033
DO - 10.1590/s0004-27492007000200033
M3 - Review article
C2 - 17589716
AN - SCOPUS:34249951244
SN - 0004-2749
VL - 70
SP - 363
EP - 370
JO - Arquivos Brasileiros de Oftalmologia
JF - Arquivos Brasileiros de Oftalmologia
IS - 2
ER -