Neoplasia in the chimpanzee (Pan spp.)

S. L. Brown, D. C. Anderson, E. J. Dick, R. Guardado-Mendoza, A. P. Garcia, G. B. Hubbard

Resultado de la investigación: Articlerevisión exhaustiva

36 Citas (Scopus)


Background: Chimpanzees have over 98% genomic sequence homology with humans and may have a similar host response to malignancy. There is minimal information concerning cancer in the chimpanzee and such information would be valuable to individuals caring for and using them for research. Methods: Spontaneous neoplasia that was documented in two chimpanzee colonies and in the literature were evaluated statistically. Results: In all, 105 spontaneous and 12 experimental neoplasms were diagnosed. Seventy-four spontaneous tumors occurred in females, 24 in males, and seven in animals of undetermined sex. Of the spontaneous tumors 89 were benign, 14 were malignant, and two were undetermined. Neoplasia was most common in the urogenital system in females. Conclusions: Neoplasia is not uncommon in the chimpanzee, is generally benign, and occurs primarily in the urogenital system in females.

Idioma originalEnglish (US)
Páginas (desde-hasta)137-144
Número de páginas8
PublicaciónJournal of medical primatology
EstadoPublished - 2009

ASJC Scopus subject areas

  • Animal Science and Zoology
  • veterinary(all)


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