Molecular aspects of thyroid cancer in children

Gary L. Francis

doi:10.1007/978-1-59259-995-0_4

Molecular aspects of thyroid cancer in children

Producción científica: Chapter

Resumen

Children with thyroid cancer generally have a more favorable prognosis than adults. This chapter reviews the data that suggest the pattern of ret/PTC, BRAF, and RAS mutations might differ in papillary thyroid carcinoma (PTC) from children and adults. Expression of the insulin-like growth factors (IGFs) and IGF receptors may also differ, as well as the intensity or nature of the immune response. Additional study is warranted to better define the impact of each of these factors on the clinical behavior of thyroid cancers in children.

Idioma original	English (US)
Título de la publicación alojada	Thyroid Cancer (Second Edition)
Subtítulo de la publicación alojada	A Comprehensive Guide to Clinical Management
Editorial	Humana Press
Páginas	33-39
Número de páginas	7
ISBN (versión impresa)	9781588294623
DOI	https://doi.org/10.1007/978-1-59259-995-0_4
Estado	Published - 2006
Publicado de forma externa	Sí

ASJC Scopus subject areas

General Medicine

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10.1007/978-1-59259-995-0_4

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Molecular aspects of thyroid cancer in children

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